Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer (Q38747834)

6 September 2017

title

Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer (English)

1 reference

6 September 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Didier Meseure

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Elisabetta Marangoni

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Sudhir Varma

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

William Reinhold

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Rosine Onclercq-Delic

8

object named as

Rosine Onclercq-Delic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Hamza Mameri

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Géraldine Buhagiar-Labarchède

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

André Nicolas

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Vinodh Rajapakse

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Mounira Amor-Guéret

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Sophie Vacher

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Yves Pommier

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

6 September 2016

1 reference

6 September 2017

published in

Clinical Cancer Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

2116-2126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27601591%20AND%20SRC:MED&resulttype=core&format=json

Increased CDA expression/activity in males contributes to decreased cytidine analog half-life and likely contributes to worse outcomes with 5-azacytidine or decitabine therapy

31 May 2020

cites work

1 reference

12 December 2020

Purification of human cytidine deaminase: Molecular and enzymatic characterization and inhibition by synthetic pyrimidine analogs

1 reference

12 December 2020

Gemcitabine pharmacogenomics: cytidine deaminase and deoxycytidylate deaminase gene resequencing and functional genomics

1 reference

12 December 2020

Metabolism of cytosine arabinoside in Tetrahymena pyriformis

1 reference

12 December 2020

Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases.

1 reference

12 December 2020

Cytidine deaminase genotype and toxicity of cytosine arabinoside therapy in children with acute myeloid leukemia

1 reference

12 December 2020

Poisoning Cancer Cells with Oxidized Nucleosides.

1 reference

12 December 2020

Role of cytidine deaminase in toxicity and efficacy of nucleosidic analogs

1 reference

12 December 2020

5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

1 reference

12 December 2020

Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288).

1 reference

12 December 2020

Single nucleotide polymorphisms of gemcitabine metabolic genes and pancreatic cancer survival and drug toxicity

1 reference

12 December 2020

The AID/APOBEC family of nucleic acid mutators.

1 reference

12 December 2020

Using CellMiner 1.6 for Systems Pharmacology and Genomic Analysis of the NCI-60

1 reference

12 December 2020

Activation of aminoflavone (NSC 686288) by a sulfotransferase is required for the antiproliferative effect of the drug and for induction of histone gamma-H2AX.

1 reference

12 December 2020

DNA fingerprinting of the NCI-60 cell line panel

1 reference

12 December 2020

Identification of functional single nucleotide polymorphism haplotypes in the cytidine deaminase promoter

1 reference

12 December 2020

Isolation and characterization of the gene coding for human cytidine deaminase

1 reference

12 December 2020

Aryl hydrocarbon receptor activation of an antitumor aminoflavone: basis of selective toxicity for MCF-7 breast tumor cells.

1 reference

12 December 2020

TIPIN depletion leads to apoptosis in breast cancer cells

1 reference

12 December 2020

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade

1 reference

12 December 2020

Forced expression of cytidine deaminase confers resistance to cytosine arabinoside and gemcitabine

1 reference

12 December 2020

A new model of patient tumor-derived breast cancer xenografts for preclinical assays

1 reference

12 December 2020

SNP analyses in cytarabine metabolizing enzymes in AML patients and their impact on treatment response and patient survival: identification of CDA SNP C-451T as an independent prognostic parameter for survival.

1 reference

12 December 2020

Influence of cytidine deaminase on antitumor activity of 2'-deoxycytidine analogs in vitro and in vivo

1 reference

12 December 2020

Aminoflavone, a ligand of the aryl hydrocarbon receptor, inhibits HIF-1alpha expression in an AhR-independent fashion.

1 reference

12 December 2020

A functional single-nucleotide polymorphism in the human cytidine deaminase gene contributing to ara-C sensitivity.

1 reference

12 December 2020

Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome

1 reference

12 December 2020

Cytidine Deaminase Axis Modulated by miR-484 Differentially Regulates Cell Proliferation and Chemoresistance in Breast Cancer.

1 reference

12 December 2020

Aminoflavone induces oxidative DNA damage and reactive oxidative species-mediated apoptosis in breast cancer cells

1 reference

12 December 2020

Cytidine deaminase residual activity in serum is a predictive marker of early severe toxicities in adults after gemcitabine-based chemotherapies

1 reference

12 December 2020

Gemcitabine resistant pancreatic cancer cell lines acquire an invasive phenotype with collateral hypersensitivity to histone deacetylase inhibitors.

1 reference

12 December 2020

Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism

1 reference

12 December 2020

The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

1 reference

12 December 2020

DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells

1 reference

12 December 2020

Genomic polymorphisms provide prognostic information in intermediate-risk acute myeloblastic leukemia.

1 reference

12 December 2020

Reactivation of estrogen receptor α by vorinostat sensitizes mesenchymal-like triple-negative breast cancer to aminoflavone, a ligand of the aryl hydrocarbon receptor

1 reference

12 December 2020

CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer

1 reference

12 December 2020

Macrophages mediate gemcitabine resistance of pancreatic adenocarcinoma by upregulating cytidine deaminase

1 reference

12 December 2020

Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

1 reference

12 December 2020

Cytidine deaminase single-nucleotide polymorphism is predictive of toxicity from gemcitabine in patients with pancreatic cancer: RTOG 9704.

1 reference

12 December 2020

Cytidine deaminase genetic variants influence RNA expression and cytarabine cytotoxicity in acute myeloid leukemia

1 reference

12 December 2020

Pyrimidine Pool Disequilibrium Induced by a Cytidine Deaminase Deficiency Inhibits PARP-1 Activity, Leading to the Under Replication of DNA.

1 reference

12 December 2020

GENT: gene expression database of normal and tumor tissues

1 reference

12 December 2020

Molecular transitions from papillomavirus infection to cervical precancer and cancer: Role of stromal estrogen receptor signaling

1 reference

12 December 2020

Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugs

1 reference

12 December 2020