Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas (Q38760734)

9 January 2018

title

Combination Therapy with Anti-PD-1, Anti-TIM-3, and Focal Radiation Results in Regression of Murine Gliomas (English)

1 reference

9 January 2018

adaptive radiation therapy

main subject

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Phuoc T Tran

18

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Michael Lim

26

Michael Lim

1 reference

9 January 2018

Peter C. Burger

22

Peter C Burger

1 reference

9 January 2018

Tomas Garzon-Muvdi

14

Tomas Garzon-Muvdi

1 reference

9 January 2018

Henry Brem

24

Henry Brem

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9 January 2018

author name string

Jennifer E Kim

1

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9 January 2018

Mira A Patel

2

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9 January 2018

Antonella Mangraviti

3

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9 January 2018

Eileen S Kim

4

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9 January 2018

Debebe Theodros

5

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9 January 2018

Esteban Velarde

6

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9 January 2018

Ann Liu

7

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9 January 2018

Eric W Sankey

8

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9 January 2018

Ada Tam

9

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9 January 2018

Haiying Xu

10

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9 January 2018

Dimitrios Mathios

11

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9 January 2018

Christopher M Jackson

12

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9 January 2018

Sarah Harris-Bookman

13

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9 January 2018

Mary Sheu

15

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9 January 2018

Allison M Martin

16

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9 January 2018

Betty M Tyler

17

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9 January 2018

Xiaobu Ye

19

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9 January 2018

Alessandro Olivi

20

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9 January 2018

Janis M Taube

21

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9 January 2018

Charles G Drake

23

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9 January 2018

Drew M Pardoll

25

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9 January 2018

language of work or name

English

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publication date

29 June 2016

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9 January 2018

published in

Clinical Cancer Research

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9 January 2018

volume

23

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9 January 2018

issue

1

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9 January 2018

page(s)

124-136

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9 January 2018

Expression of the galectin-9-Tim-3 pathway in glioma tissues is associated with the clinical manifestations of glioma.

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Combined TIM-3 blockade and CD137 activation affords the long-term protection in a murine model of ovarian cancer

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TIM3(+)FOXP3(+) regulatory T cells are tissue-specific promoters of T-cell dysfunction in cancer

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Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomas

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Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

23 June 2018

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Potential role for STAT3 inhibitors in glioblastoma

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Human antitumor CD8+ T cells producing Th1 polycytokines show superior antigen sensitivity and tumor recognition

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Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma

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23 June 2018

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Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia

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Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

23 June 2018

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23 June 2018

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23 June 2018

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Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells

23 June 2018

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Combining radiotherapy and immunotherapy: a revived partnership

23 June 2018

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Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity

23 June 2018

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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells

23 June 2018

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The role of STAT3 activation in modulating the immune microenvironment of GBM.

23 June 2018

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Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived TGF-β.

31 August 2018

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Prognostic significance and mechanism of Treg infiltration in human brain tumors.

31 August 2018

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Induction of inhibitory central nervous system-derived and stimulatory blood-derived dendritic cells suggests a dual role for granulocyte-macrophage colony-stimulating factor in central nervous system inflammation

31 August 2018

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A virtual frame system for stereotactic radiosurgery planning

31 August 2018

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CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo

31 August 2018

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31 August 2018

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31 August 2018

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10.1158/1078-0432.CCR-15-1535

4 November 2018

Identifiers

DOI

1 reference

9 January 2018

PMC publication ID

5735836

1 reference

9 January 2018

PubMed publication ID

27358487

1 reference

9 January 2018