B and T cell antigen receptor repertoires in lupus/arthritis murine models (Q38760990)

6 September 2017

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title

B and T cell antigen receptor repertoires in lupus/arthritis murine models (English)

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6 September 2017

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A N Theofilopoulos

1

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6 September 2017

P A Singer

2

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6 September 2017

R Kofler

3

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6 September 2017

D H Kono

4

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6 September 2017

M A Duchosal

5

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6 September 2017

R S Balderas

6

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6 September 2017

publication date

1 January 1989

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Seminars in Immunopathology

6 September 2017

published in

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6 September 2017

volume

11

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6 September 2017

issue

3

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6 September 2017

page(s)

335-368

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Effects of thymectomy or androgen administration upon the autoimmune disease of MRL/Mp-lpr/lpr mice

6 September 2017

cites work

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12 December 2020

The T-cell repertoire is heavily influenced by tolerance to polymorphic self-antigens

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12 December 2020

Classification of mouse VK groups based on the partial amino acid sequence to the first invariant tryptophan: impact of 14 new sequences from IgG myeloma proteins

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12 December 2020

Preventive effect of monoclonal anti-L3T4 antibody on development of diabetes in NOD mice

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12 December 2020

The lymphoproliferating cells of MRL-lpr/lpr mice are a polyclonal population that bear the T lymphocyte receptor for antigen.

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12 December 2020

Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes

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12 December 2020

Variable region sequences of murine IgM anti-IgG monoclonal autoantibodies (rheumatoid factors). A structural explanation for the high frequency of IgM anti-IgG B cells

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12 December 2020

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

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12 December 2020

Genetics and strain distribution of concanavalin A-reactive Ly-2-, L3T4- peripheral precursors of autoreactive T cells.

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12 December 2020

The immunoglobulin heavy chain variable region (Igh-V) locus in the mouse. I. One hundred Igh-V genes comprise seven families of homologous genes

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12 December 2020

Spontaneous murine lupus-like syndromes. Clinical and immunopathological manifestations in several strains

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12 December 2020

Relationship of human variable region heavy chain germ-line genes to genes encoding anti-DNA autoantibodies

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12 December 2020

B cell dependence on and response to accessory signals in murine lupus strains

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12 December 2020

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12 December 2020

Two V kappa germ-line genes related to the GAT idiotypic network (Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse V kappa-1 variability subgroup.

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12 December 2020

T lymphocytes in collagen II-induced arthritis in mice. Characterization of arthritogenic collagen II-specific T-cell lines and clones

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12 December 2020

Immunologic abnormality in NZB/NZW F1 mice. Thymus-independent occurrence of B cell abnormality and requirement for T cells in the development of autoimmune disease, as evidenced by an analysis of the athymic nude individuals

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12 December 2020

T-cell receptor alpha-chain variable-region haplotypes of normal and autoimmune laboratory mouse strains

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12 December 2020

Major histocompatibility complex class I-specific cytolytic T cells, derived from gld mice, lacking Thy-1, CD4, and CD8.

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12 December 2020

Origin of autoreactive T helper cells. I. Characterization of Thy-1+, Lyt-, L3T4- precursors in the spleen of normal mice.

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12 December 2020

The Mls locus: new clues to a lingering mystery

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12 December 2020

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis

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12 December 2020

Positive selection of antigen-specific T cells in thymus by restricting MHC molecules

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12 December 2020

Accessories or coreceptors?

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12 December 2020

Induction of severe autoimmune disease in normal mice by simultaneous action of multiple immunostimulators

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12 December 2020

Deletion of self-reactive thymocytes occurs at a CD4+8+ precursor stage

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12 December 2020

Clonal diversity and T-cell receptor beta-chain variable gene expression in enlarged lymph nodes of MRL-lpr/lpr lupus mice

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12 December 2020

Intrathymic deletion of self-reactive cells prevented by neonatal anti-CD4 antibody treatment

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12 December 2020

Somatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 mice

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12 December 2020

Murine models of systemic lupus erythematosus

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12 December 2020

Idiotypes and diseases

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12 December 2020

Influence of thymic genotype on the systemic lupus erythematosus-like disease and T cell proliferation of MRL/Mp-lpr/lpr mice

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12 December 2020

The genetic origin of autoantibodies

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12 December 2020

The Ig germline gene repertoire: economy or wastage?

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12 December 2020

Eleven MRL-lpr/lpr anti-DNA autoantibodies are encoded by genes from four VH gene families: a potentially biased usage of VH genes.

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12 December 2020

A single germline VH gene segment of normal A/J mice encodes autoantibodies characteristic of systemic lupus erythematosus

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12 December 2020

VH gene expression is restricted in anti-IgG antibodies from MRL autoimmune mice

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12 December 2020

Independent segregation of NZB immune abnormalities in NZB x C58 recombinant inbred mice

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12 December 2020

A novel population of T-cell receptor alpha beta-bearing thymocytes which predominantly expresses a single V beta gene family

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12 December 2020

Self-tolerance eliminates T cells specific for Mls-modified products of the major histocompatibility complex

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12 December 2020

The Mls system: non-MHC genes that encode strong T-cell stimulatory determinants

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12 December 2020

Genetic diversity of murine rheumatoid factors

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12 December 2020

A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody

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12 December 2020

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

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12 December 2020

Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

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12 December 2020

T-cell antigen receptor genes and T-cell recognition

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12 December 2020

Reversal of experimental allergic encephalomyelitis with monoclonal antibody to a T-cell subset marker

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12 December 2020

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4.

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12 December 2020

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

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12 December 2020

Molecular analysis of the murine lupus-associated anti-self response: involvement of a large number of heavy and light chain variable region genes

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12 December 2020

A large deletion within the T-cell receptor beta-chain gene complex in New Zealand white mice

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12 December 2020

The T-cell repertoire for antigen and MHC.

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12 December 2020

Does the deletion within T cell receptor β-chain gene of NZW mice contribute to autoimmunity in (NZB × NZW)F1mice?

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12 December 2020

V region sequences of anti-DNA and anti-RNA autoantibodies from NZB/NZW F1 mice.

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12 December 2020

Structural and functional implications of a restricted antibody response to a defined antigenic region on the influenza virus hemagglutinin.

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12 December 2020

The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition

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12 December 2020

Members of novel VH gene families are found in VDJ regions of polyclonally activated B-lymphocytes

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12 December 2020

Functional and molecular studies of V genes expressed in autoantibodies

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12 December 2020

Specificity and molecular characteristics of monoclonal IgM rheumatoid factors from arthritic and non-arthritic mice.

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12 December 2020

Somatic generation of antibody diversity

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12 December 2020

Differentiation potential of subsets of CD4-8- thymocytes

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12 December 2020

T-cell-receptor beta- and I-A beta-chain genes of normal SWR mice are linked with the development of lupus nephritis in NZB x SWR crosses

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12 December 2020

Genetic elements used for a murine lupus anti-DNA autoantibody are closely related to those for antibodies to exogenous antigens

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12 December 2020

Molecular genetics of murine lupus models

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12 December 2020

Developmental status and reconstitution potential of subpopulations of murine thymocytes

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12 December 2020

Molecular aspects of murine systemic lupus erythematosus

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12 December 2020

Thymus and autoimmunity. Transplantation of the thymus from cyclosporin A-treated mice causes organ-specific autoimmune disease in athymic nude mice

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12 December 2020

Structure, organization and polymorphism of murine and human T-cell receptor alpha and beta chain gene families

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12 December 2020

The heavy chain genes of a lupus anti-DNA autoantibody are encoded in the germ line of a nonautoimmune strain of mouse and conserved in strains of mice polymorphic for this gene locus.

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12 December 2020

Immunoglobulin kappa light chain variable region gene complex organization and immunoglobulin genes encoding anti-DNA autoantibodies in lupus mice

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12 December 2020

Development of autoreactive L3T4+ T cells from double-negative (L3T4-/Ly-2-) Thy-1+ spleen cells of normal mice

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12 December 2020

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

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12 December 2020

Isolation and characterization of a light chain variable region gene for human rheumatoid factors

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12 December 2020

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice.

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12 December 2020

Molecular basis for the nonexpression of V beta 17 in some strains of mice

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12 December 2020

T lymphocyte line specific for thyroglobulin produces or vaccinates against autoimmune thyroiditis in mice

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12 December 2020

Preferential expression of the T-cell receptor Vβ3 gene by Mlsc reactive T cells

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12 December 2020

Molecular and cellular events of T cell development

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12 December 2020

One heavy chain variable region gene segment subfamily in the BALB/c mouse contains 500-1000 or more members

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12 December 2020

Immunotherapy for myasthenia gravis: a murine model

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12 December 2020

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

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12 December 2020

Ig heavy chain variable region gene complex of lupus mice exhibits normal restriction fragment length polymorphism

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12 December 2020

The genetic origin of murine lupus-associated autoantibodies

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12 December 2020

Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis

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12 December 2020

Characterization and differentiation of CD4-, CD8- thymocytes sorted with the Ly-24 marker

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12 December 2020

Alloreactive cytolytic T cell clones with dual recognition of HLA-B27 and HLA-DR2 antigens. Selective involvement of CD8 in their class I--directed cytotoxicity

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12 December 2020

The Ig kappa L chain allelic groups among the Ig kappa haplotypes and Ig kappa crossover populations suggest a gene order

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12 December 2020

Molecular characterization of T-cell antigen receptor expression by subsets of CD4- CD8- murine thymocytes

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12 December 2020

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination.

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12 December 2020

Function and specificity of T cell subsets in the mouse

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12 December 2020

Self-tolerance alters T-cell receptor expression in an antigen-specific MHC restricted immune response

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12 December 2020

The contribution of NZW genes to lupus-like disease in (NZB x NZW)F1 mice

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12 December 2020

Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease

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12 December 2020

Identity of cells that imprint H-2-restricted T-cell specificity in the thymus

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12 December 2020

Phenotypic properties, interleukin 2 production, and developmental origin of a "mature" subpopulation of Lyt-2- L3T4- mouse thymocytes

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12 December 2020

Growth and differentiation in vitro of the accumulating Lyt-2-/L3T4- subset in lpr mice

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12 December 2020

Identification of a B cell differentiation factor(s) spontaneously produced by proliferating T cells in murine lupus strains of the lpr/lpr genotype

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12 December 2020

Evolution of antibody variable region structure during the immune response

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12 December 2020

Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis

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12 December 2020

Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes

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12 December 2020

Shared idiotypes and restricted immunoglobulin variable region heavy chain genes characterize murine autoantibodies of various specificities

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12 December 2020

Delineation of a defect in T cell receptor beta genes of NZW mice predisposed to autoimmunity

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12 December 2020

The mouse immunoglobulin heavy-chain enhancer: effect on transcription in vitro and binding of proteins present in HeLa and lymphoid B cell extracts

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12 December 2020

The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL-lpr/lpr mice

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12 December 2020

Prevention of type II collagen-induced arthritis by in vivo treatment with anti-L3T4

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12 December 2020

Murine T-cell receptor mutants with deletions of beta-chain variable region genes

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12 December 2020

Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity

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12 December 2020

The MHC molecule I-E is necessary but not sufficient for the clonal deletion of V beta 11-bearing T cells

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12 December 2020

Deletion of potentially self-reactive T cell receptor specificities in L3T4-, Lyt-2- T cells of lpr mice

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12 December 2020

Structure, function, and serology of the T-cell antigen receptor complex

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12 December 2020

Abnormal expression of T cell receptor genes in Lyt-2- L3T4- lymphocytes of lpr mice: comparison with normal immature thymocytes

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12 December 2020

The role of clonal selection and somatic mutation in autoimmunity

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12 December 2020

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

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12 December 2020

A member of a new VH gene family encodes antibromelinized mouse red blood cell autoantibodies

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12 December 2020

T cell selection in the thymus

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12 December 2020

Genomic organization of the mouse T-cell receptor beta-chain gene family

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12 December 2020

Different VL and VH germ-line genes are used to produce similar combining sites with specificity for alpha(1----6)dextrans.

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12 December 2020

V genes encoding autoantibodies: molecular and phenotypic characteristics

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12 December 2020

The Igh-V locus of MRL mice: restriction fragment length polymorphism in eleven strains of mice as determined with VH and D gene probes

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12 December 2020

Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

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12 December 2020

Virus-induced diabetes mellitus. XX. Polyendocrinopathy and autoimmunity.

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12 December 2020

Novel V genes encode virtually identical variable regions of six murine monoclonal anti-bromelain-treated red blood cell autoantibodies

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12 December 2020

Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice

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12 December 2020

T cell tolerance by clonal elimination in the thymus

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12 December 2020

Regulation of genome rearrangement events during lymphocyte differentiation

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12 December 2020

A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation. Preferential formation of autoantibodies characteristic of SLE

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12 December 2020

A new murine Ig VH gene family

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12 December 2020

Relative V beta transcript levels in thymus and peripheral lymphoid tissues from various mouse strains. Inverse correlation of I-E and Mls expression with relative abundance of several V beta transcripts in peripheral lymphoid tissues

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12 December 2020

Complexity, polymorphism, and connectivity of mouse Vk gene families

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12 December 2020

Homology of the NH2-terminal amino acid sequences of the heavy and light chains of human monoclonal lupus autoantibodies containing the dominant 16/6 idiotype

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12 December 2020

T-cell receptor V beta use predicts reactivity and tolerance to Mlsa-encoded antigens

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12 December 2020

Thymic major histocompatibility complex antigens and the αβ T-cell receptor determine the CD4/CD8 phenotype of T cells

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12 December 2020

Identifiers

DOI

10.1007/BF00197311

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Dimensions Publication ID

6 September 2017

1013336457

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