SIRT1 prevents hyperuricemia via the PGC-1α/PPARγ-ABCG2 pathway (Q38782662)

6 September 2017

SIRT1 prevents hyperuricemia via the PGC-1α/PPARγ-ABCG2 pathway (English)

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6 September 2017

Juan Wang

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6 September 2017

Xiao-Xia Zhu

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6 September 2017

Lei Liu

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6 September 2017

Yu Xue

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6 September 2017

Xue Yang

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6 September 2017

He-Jian Zou

6

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6 September 2017

29 March 2016

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6 September 2017

53

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2

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443-452

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https://scigraph.springernature.com/pub.10.1007/s12020-016-0896-7

6 September 2017

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Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy

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Mechanism of human SIRT1 activation by resveratrol

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Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice

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Peroxisome-Proliferator-Activated Receptor δ Activates Fat Metabolism to Prevent Obesity

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Study on the correlation between constituents detected in serum from Rhizoma Smilacis Glabrae and the reduction of uric acid levels in hyperuricemia

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Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase

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Reactive oxygen species derived from xanthine oxidase interrupt dimerization of breast cancer resistance protein, resulting in suppression of uric acid excretion to the intestinal lumen

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Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

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SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

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Resveratrol improves health and survival of mice on a high-calorie diet

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Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

21 January 2018

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The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

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Fasting promotes the expression of SIRT1, an NAD+ -dependent protein deacetylase, via activation of PPARalpha in mice.

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PPARbeta/delta regulates the human SIRT1 gene transcription via Sp1.

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Nuclear receptor corepressors and PPARgamma

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ABCG2 is a high-capacity urate transporter and its genetic impairment increases serum uric acid levels in humans

21 January 2018

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12 December 2020

The effect of resveratrol on the recurrent attacks of gouty arthritis

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12 December 2020

Role of the peroxisome proliferator-activated receptor (PPAR) in mediating the effects of fibrates and fatty acids on gene expression

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12 December 2020

Anti-hyperuricemic and nephroprotective effects of Smilax china L

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12 December 2020

10.1007/S12020-016-0896-7

Identifiers

DOI

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6 September 2017

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