Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif. (Q38784489)

From Wikidata

Jump to navigation Jump to search

scientific article published on 17 March 2016

Language	Label	Description	Also known as
English	Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif.	scientific article published on 17 March 2016

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Alzheimer's disease

0 references

Ramón Soto-Otero

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Leonardo Pisani

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Giuseppe Felice Mangiatordi

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Orazio Nicolotti

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

10

object named as

Angelo Carotti

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

author name string

Roberta Farina

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Nunzio Denora

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Estefania Mendez-Alvarez

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

Cosimo Damiano Altomare

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

language of work or name

0 references

publication date

17 March 2016

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

21

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

362

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

copyright license

Creative Commons Attribution 4.0 International

17 March 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Alzheimer's Disease

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Cholinesterase inhibitors stabilize Alzheimer disease

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

The molecular basis of memantine action in Alzheimer's disease and other neurologic disorders: low-affinity, uncompetitive antagonism

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

The multifactorial nature of Alzheimer's disease for developing potential therapeutics.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Recent advances in the multitarget-directed ligands approach for the treatment of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Successes and failures for drugs in late-stage development for Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Monoamine oxidase-B inhibition in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Fine molecular tuning at position 4 of 2H-chromen-2-one derivatives in the search of potent and selective monoamine oxidase B inhibitors.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

In silico design of novel 2H-chromen-2-one derivatives as potent and selective MAO-B inhibitors.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Structure-Based Design and Optimization of Multitarget-Directed 2H-Chromen-2-one Derivatives as Potent Inhibitors of Monoamine Oxidase B and Cholinesterases.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Design, synthesis, and biological evaluation of coumarin derivatives tethered to an edrophonium-like fragment as highly potent and selective dual binding site acetylcholinesterase inhibitors

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Synthesis and biological evaluation of scopoletin derivatives

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

A new and rapid colorimetric determination of acetylcholinesterase activity

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Discovery, biological evaluation, and structure-activity and -selectivity relationships of 6'-substituted (E)-2-(benzofuran-3(2H)-ylidene)-N-methylacetamides, a novel class of potent and selective monoamine oxidase inhibitors.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Mitochondrial complex I inhibitor rotenone induces apoptosis through enhancing mitochondrial reactive oxygen species production

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Translocator protein (TSPO) ligand-Ara-C (cytarabine) conjugates as a strategy to deliver antineoplastic drugs and to enhance drug clinical potential

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Novel codrugs with GABAergic activity for dopamine delivery in the brain

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Design, synthesis, and 3D QSAR of novel potent and selective aromatase inhibitors.

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Binding of rasagiline-related inhibitors to human monoamine oxidases: a kinetic and crystallographic analysis

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Propargylamine as functional moiety in the design of multifunctional drugs for neurodegenerative disorders: MAO inhibition and beyond

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Discovery of a Novel Class of Potent Coumarin Monoamine Oxidase B Inhibitors: Development and Biopharmacological Profiling of 7-[(3-Chlorobenzyl)oxy]-4-[(methylamino)methyl]-2H-chromen-2-one Methanesulfonate (NW-1772) as a Highly Potent, Selective, R

1 reference

https://api.crossref.org/works/10.3390%2FMOLECULES21030362

21 January 2018

Inhibition of brain monoamine oxidase by adducts of 1,2,3,4-tetrahydroisoquinoline with components of cigarette smoke

1 reference

https://pubmed.ncbi.nlm.nih.gov/26999091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/MOLECULES21030362

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26999091%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q38784489&oldid=1880491662"