ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. (Q38834012)

6 September 2017

ATR Plays a Direct Antiapoptotic Role at Mitochondria, which Is Regulated by Prolyl Isomerase Pin1. (English)

1 reference

6 September 2017

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26387736%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Phillip R Musich

3

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2 June 2020

Moises A Serrano

6

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2 June 2020

author name string

Benjamin A Hilton

1

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2 June 2020

Hui Wang

4

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2 June 2020

Brian M Cartwright

5

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2 June 2020

Xiao Zhen Zhou

7

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2 June 2020

Kun Ping Lu

8

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2 June 2020

Yue Zou

9

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2 June 2020

publication date

16 September 2015

1 reference

6 September 2017

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2 June 2020

volume

60

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2 June 2020

issue

1

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2 June 2020

page(s)

35-46

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The I-TASSER Suite: protein structure and function prediction.

2 June 2020

cites work

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ATM and ATR as therapeutic targets in cancer

9 September 2017

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Regulation of mitochondrial apoptosis by Pin1 in cancer and neurodegeneration

9 September 2017

1 reference

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Prolyl isomerase Pin1 in cancer

9 September 2017

1 reference

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ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress

9 September 2017

1 reference

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PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.

9 September 2017

1 reference

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Causes and consequences of replication stress

9 September 2017

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Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis

9 September 2017

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Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection

9 September 2017

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Regulation of cardiac hypertrophic signaling by prolyl isomerase Pin1

9 September 2017

1 reference

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Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis

9 September 2017

1 reference

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Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease

9 September 2017

1 reference

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The DNA damage response and cancer therapy

9 September 2017

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Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR

9 September 2017

1 reference

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Prolyl isomerase Pin1 as a molecular switch to determine the fate of phosphoproteins

9 September 2017

1 reference

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Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase

9 September 2017

1 reference

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ATR autophosphorylation as a molecular switch for checkpoint activation.

9 September 2017

1 reference

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Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase

9 September 2017

1 reference

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Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function

9 September 2017

1 reference

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Pin1: A New Genetic Link between Alzheimers Disease, Cancer and Aging

9 September 2017

1 reference

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Mitochondria and cell death: outer membrane permeabilization and beyond

9 September 2017

1 reference

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Mouse models for ATR deficiency

9 September 2017

1 reference

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Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution

9 September 2017

1 reference

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Bid: a Bax-like BH3 protein.

9 September 2017

1 reference

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ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine

9 September 2017

1 reference

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BCL-2 family antagonists for cancer therapy

9 September 2017

1 reference

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ATR: an essential regulator of genome integrity

9 September 2017

1 reference

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

9 September 2017

1 reference

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Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation

9 September 2017

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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

9 September 2017

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9 September 2017

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

9 September 2017

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An electronic effect on protein structure.

9 September 2017

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The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

9 September 2017

1 reference

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ATR and ATRIP: partners in checkpoint signaling

9 September 2017

1 reference

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Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

9 September 2017

1 reference

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ATR disruption leads to chromosomal fragmentation and early embryonic lethality

9 September 2017

1 reference

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The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

9 September 2017

1 reference

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Solution structure of the proapoptotic molecule BID: a structural basis for apoptotic agonists and antagonists

9 September 2017

1 reference

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Solution structure of BID, an intracellular amplifier of apoptotic signaling

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4592481

The Bcl-2 protein family: arbiters of cell survival

9 September 2017

1 reference

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Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

9 September 2017

1 reference

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A helix propensity scale based on experimental studies of peptides and proteins

9 September 2017

1 reference

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A human peptidyl-prolyl isomerase essential for regulation of mitosis

9 September 2017

1 reference

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Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides

9 September 2017

1 reference

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The mechanism of protein folding. Implications of in vitro refolding models for de novo protein folding and translocation in the cell

9 September 2017

1 reference

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The human MSH5 (MutSHomolog 5) protein localizes to mitochondria and protects the mitochondrial genome from oxidative damage

9 September 2017

1 reference

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A role for proapoptotic BID in the DNA-damage response

9 September 2017

1 reference

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Inhibition of Pro-apoptotic BAX by a noncanonical interaction mechanism.

14 September 2017

1 reference

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Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF(betatrcp).

25 September 2017

1 reference

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The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer.

22 August 2018

1 reference

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The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response.

22 August 2018

1 reference

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Prolyl isomerases and nuclear function

22 August 2018

1 reference

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Organelle isolation: functional mitochondria from mouse liver, muscle and cultured filroblasts

22 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26387736

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2015.08.008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26387736%20AND%20SRC:MED&resulttype=core&format=json

release_nza5u4zlizdi3m75cn2b6qsh5i

2 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/nza5u4zlizdi3m75cn2b6qsh5i

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26387736%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

26387736

1 reference