Intra- and trans-cellular delivery of enzymes by direct conjugation with non-multivalent anti-ICAM molecules (Q38836304)

4 March 2018

title

Intra- and trans-cellular delivery of enzymes by direct conjugation with non-multivalent anti-ICAM molecules (English)

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4 March 2018

author name string

Rasa Ghaffarian

1

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4 March 2018

Niksa Roki

2

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4 March 2018

Abraham Abouzeid

3

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4 March 2018

Wyatt Vreeland

4

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4 March 2018

Silvia Muro

5

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4 March 2018

language of work or name

English

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publication date

26 July 2016

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4 March 2018

Journal of Controlled Release

published in

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4 March 2018

volume

238

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4 March 2018

page(s)

221-230

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4 March 2018

Targeting, endocytosis, and lysosomal delivery of active enzymes to model human neurons by ICAM-1-targeted nanocarriers.

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17 June 2018

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A DNA-Device that Mediates Selective Endosomal Escape and Intracellular Delivery of Drugs and Biologicals

17 June 2018

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Strategies for delivery of therapeutics into the central nervous system for treatment of lysosomal storage disorders

17 June 2018

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Specific binding, uptake, and transport of ICAM-1-targeted nanocarriers across endothelial and subendothelial cell components of the blood-brain barrier

17 June 2018

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Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor

17 June 2018

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Comparative binding, endocytosis, and biodistribution of antibodies and antibody-coated carriers for targeted delivery of lysosomal enzymes to ICAM-1 versus transferrin receptor

17 June 2018

1 reference

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Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: opportunities and challenges.

17 June 2018

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Challenges in design and characterization of ligand-targeted drug delivery systems

17 June 2018

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Transport of nanocarriers across gastrointestinal epithelial cells by a new transcellular route induced by targeting ICAM-1.

17 June 2018

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Intercellular adhesion molecule 1 engagement modulates sphingomyelinase and ceramide, supporting uptake of drug carriers by the vascular endothelium

17 June 2018

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A fibrinogen-derived peptide provides intercellular adhesion molecule-1-specific targeting and intraendothelial transport of polymer nanocarriers in human cell cultures and mice

17 June 2018

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Enhanced delivery of α-glucosidase for Pompe disease by ICAM-1-targeted nanocarriers: comparative performance of a strategy for three distinct lysosomal storage disorders

17 June 2018

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Folate-targeted therapies for cancer

17 June 2018

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Subcellular targeting strategies for drug design and delivery

17 June 2018

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Strategies to advance translational research into brain barriers

17 June 2018

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PLGA nanoparticle--peptide conjugate effectively targets intercellular cell-adhesion molecule-1.

17 June 2018

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Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung

17 June 2018

1 reference

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Targeted ultrasound contrast agents: In vitro assessment of endothelial dysfunction and multi-targeting to ICAM-1 and sialyl Lewisx

17 June 2018

1 reference

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A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1.

17 June 2018

1 reference

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Caveolae: from basic trafficking mechanisms to targeting transcytosis for tissue-specific drug and gene delivery in vivo

17 June 2018

1 reference

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Cellular uptake of liposomes targeted to intercellular adhesion molecule-1 (ICAM-1) on bronchial epithelial cells

17 June 2018

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Dimerization of the polymeric immunoglobulin receptor controls its transcytotic trafficking

17 June 2018

1 reference

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Oligomerized transferrin receptors are selectively retained by a lumenal sorting signal in a long-lived endocytic recycling compartment

17 June 2018

1 reference

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Internalization and degradation of macrophage Fc receptors bound to polyvalent immune complexes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5830118

Endothelial targeting of high-affinity multivalent polymer nanocarriers directed to intercellular adhesion molecule 1.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5830118

Characterization of endothelial internalization and targeting of antibody-enzyme conjugates in cell cultures and in laboratory animals

22 August 2018

1 reference

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Endocytosis pathways in endothelium: how many?

22 August 2018

1 reference

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Inflammation-specific T1 imaging using anti-intercellular adhesion molecule 1 antibody-conjugated gadolinium diethylenetriaminepentaacetic acid

2 December 2018

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12 December 2020

Chitosan-Alginate Blended Nanoparticles as Carriers for the Transmucosal Delivery of Macromolecules

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12 December 2020

ICAM-directed vascular immunotargeting of antithrombotic agents to the endothelial luminal surface

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12 December 2020

Delivery of Acid Sphingomyelinase in Normal and Niemann-Pick Disease Mice Using Intercellular Adhesion Molecule-1-Targeted Polymer Nanocarriers

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12 December 2020

Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting

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12 December 2020

10.1016/J.JCONREL.2016.07.042

Identifiers

DOI

1 reference

4 March 2018

PMCID

5830118

1 reference

4 March 2018

PubMed ID

27473764

1 reference

4 March 2018