Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition (Q38840559)

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scientific article published on 27 August 2015

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English	Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition	scientific article published on 27 August 2015

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scholarly article

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Europe PubMed Central

6 September 2017

Quantitative proteomic analysis reveals maturation as a mechanism underlying glucocorticoid resistance in B lineage ALL and re-sensitization by JNK inhibition (English)

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Europe PubMed Central

6 September 2017

glucocorticoid resistance

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Johannes Rainer

10

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1 June 2020

Christine J Harrison

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Christopher Redfern

14

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Anthony D Whetton

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Lindsay Nicholson

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Caroline A Evans

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Elizabeth Matheson

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Lynne Minto

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Christopher Keilty

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Maryna Sanichar

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Marian Case

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1 June 2020

Claire Schwab

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Daniel Williamson

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Reinhard Kofler

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Andrew G Hall

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Julie A E Irving

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1 June 2020

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27 August 2015

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6 September 2017

British Journal of Haematology

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1 June 2020

171

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595-605

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1 June 2020

4

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1 June 2020

Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia

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Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?

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Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

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Variable breakpoints target PAX5 in patients with dicentric chromosomes: a model for the basis of unbalanced translocations in cancer

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CD20 up-regulation in pediatric B-cell precursor acute lymphoblastic leukemia during induction treatment: setting the stage for anti-CD20 directed immunotherapy

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Regulation of Pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors

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The transcriptional regulation of B cell lineage commitment.

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9 September 2017

Pax5: the guardian of B cell identity and function

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Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

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9 September 2017

Glucocorticoid-induced apoptosis and glucocorticoid resistance: molecular mechanisms and clinical relevance.

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9 September 2017

Changes in gene expression profiles in developing B cells of murine bone marrow

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9 September 2017

Glucocorticosteroid therapy in childhood acute lymphoblastic leukemia

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9 September 2017

Thymus-derived glucocorticoids regulate antigen-specific positive selection

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Cloning and expression of mutant glucocorticoid receptors from glucocorticoid-sensitive and -resistant human leukemic cells.

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

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9 September 2017

Research resource: transcriptional response to glucocorticoids in childhood acute lymphoblastic leukemia

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9 September 2017

NFkappaB modulators in a model of glucocorticoid resistant, childhood acute lymphoblastic leukemia.

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14 September 2017

ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling

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14 September 2017

Converting cell lines representing hematological malignancies from glucocorticoid-resistant to glucocorticoid-sensitive: signaling pathway interactions

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14 September 2017

Activation of the JNK pathway promotes phosphorylation and degradation of BimEL--a novel mechanism of chemoresistance in T-cell acute lymphoblastic leukemia

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14 September 2017

Glucocorticoid resistance in two key models of acute lymphoblastic leukemia occurs at the level of the glucocorticoid receptor

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14 September 2017

Loss of heterozygosity and somatic mutations of the glucocorticoid receptor gene are rarely found at relapse in pediatric acute lymphoblastic leukemia but may occur in a subpopulation early in the disease course

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14 September 2017

Immunophenotypic cell lineage and in vitro cellular drug resistance in childhood relapsed acute lymphoblastic leukaemia

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Quantitative proteomic analysis using isobaric protein tags enables rapid comparison of changes in transcript and protein levels in transformed cells

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Groucho suppresses Pax2 transactivation by inhibition of JNK-mediated phosphorylation

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DNA damage induces a novel p53-survivin signaling pathway regulating cell cycle and apoptosis in acute lymphoblastic leukemia cells

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Pathway interactions between MAPKs, mTOR, PKA, and the glucocorticoid receptor in lymphoid cells

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Anisomycin induces apoptosis of glucocorticoid resistant acute lymphoblastic leukemia CEM-C1 cells via activation of mitogen-activated protein kinases p38 and JNK.

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Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia.

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22 August 2018

Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia

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Gene expression shift towards normal B cells, decreased proliferative capacity and distinct surface receptors characterize leukemic blasts persisting during induction therapy in childhood acute lymphoblastic leukemia.

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Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia

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Early lymphoid progenitors in mouse and man are highly sensitive to glucocorticoids.

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22 August 2018

Glucocorticoid-induced apoptosis in early B cells from human bone marrow.

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22 August 2018

Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster.

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22 August 2018

Chemotherapy in 998 unselected childhood acute lymphoblastic leukemia patients. Results and conclusions of the multicenter trial ALL-BFM 86.

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22 August 2018

In vitro cellular drug resistance in children with relapsed/refractory acute lymphoblastic leukemia.

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22 August 2018

Corticosteroid resistance is increased in lymphoblasts from adults compared with children: preliminary results of in vitro drug sensitivity study in adults with acute lymphoblastic leukaemia.

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22 August 2018

Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells

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21 January 2018

Evaluation of multiplex ligation-dependent probe amplification as a method for the detection of copy number abnormalities in B-cell precursor acute lymphoblastic leukemia

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21 January 2018

Glucocorticoid-receptor-gene defects and resistance to glucocorticoid-induced apoptosis in human leukemic cell lines

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Corticosteroid-dependent reduction of leukocyte count in blood as a prognostic factor in acute lymphoblastic leukemia in childhood (therapy study ALL-BFM 83)]

1 reference

https://pubmed.ncbi.nlm.nih.gov/26310606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation between age, immunophenotype and in vitro drug resistance in 395 children with acute lymphoblastic leukemia--implications for treatment of infants

1 reference

https://pubmed.ncbi.nlm.nih.gov/26310606

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/BJH.13647

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Europe PubMed Central

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1 June 2020

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1 June 2020

1 reference

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1 June 2020

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