Poly (I: C) modulates the immunosuppressive activity of myeloid-derived suppressor cells in a murine model of breast cancer (Q38849614)

7 September 2017

title

Poly (I: C) modulates the immunosuppressive activity of myeloid-derived suppressor cells in a murine model of breast cancer (English)

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7 September 2017

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Parvin Forghani

1

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7 September 2017

Edmund K Waller

series ordinal

2

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7 September 2017

language of work or name

English

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publication date

25 July 2015

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Breast Cancer Research and Treatment

7 September 2017

published in

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7 September 2017

volume

153

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7 September 2017

issue

1

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7 September 2017

page(s)

21-30

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MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy

7 September 2017

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TLR3-mediated apoptosis and activation of phosphorylated Akt in the salivary gland epithelial cells of primary Sjögren's syndrome patients

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Myeloid-derived suppressor cells in breast cancer

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Roles of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of human prostate cancer cells

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Toll-like receptor 3 (TLR3) induces apoptosis via death receptors and mitochondria by up-regulating the transactivating p63 isoform alpha (TAP63alpha).

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TLR3 induction by anticancer drugs potentiates poly I:C-induced tumor cell apoptosis.

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A highly efficient tumor-infiltrating MDSC differentiation system for discovery of anti-neoplastic targets, which circumvents the need for tumor establishment in mice

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A novel strategy for modulation of MDSC to enhance cancer immunotherapy

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Tumor exosome-mediated MDSC activation.

21 January 2018

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Toll-like receptor (TLR) expression of immune system cells from metastatic breast cancer patients with circulating tumor cells

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Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy

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TLR3 can directly trigger apoptosis in human cancer cells.

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Anticancer function of polyinosinic-polycytidylic acid

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Silibinin inhibits accumulation of myeloid-derived suppressor cells and tumor growth of murine breast cancer

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Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice

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Regulating the suppressors: apoptosis and inflammation govern the survival of tumor-induced myeloid-derived suppressor cells (MDSC).

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Proinflammatory S100 proteins regulate the accumulation of myeloid-derived suppressor cells

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Poly I: C-activated dendritic cells that were generated in CellGro for use in cancer immunotherapy trials

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Dendritic cell maturation with poly(I:C)-based versus PGE2-based cytokine combinations results in differential functional characteristics relevant to clinical application

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Antigen-specific CD4(+) T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling

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The inflammatory cytokine tumor necrosis factor-alpha generates an autocrine tumor-promoting network in epithelial ovarian cancer cells

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The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans

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Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4

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Toll-like receptor 3 triggers apoptosis of human prostate cancer cells through a PKC-alpha-dependent mechanism.

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Polyinosinic-polycytidylic acid limits tumor outgrowth in a mouse model of metastatic lung cancer.

21 January 2018

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Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

21 January 2018

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Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease

21 January 2018

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Mechanism of tumor cell-induced T-cell apoptosis mediated by galectin-1.

21 January 2018

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Myeloid-derived suppressor cells expand during breast cancer progression and promote tumor-induced bone destruction

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10.1007/S10549-015-3508-Y

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

7 September 2017

1011637068

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