VEGF receptor signal transduction - A brief update (Q38856920)

7 September 2017

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title

VEGF receptor signal transduction - A brief update (English)

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7 September 2017

1

Lena Claesson-Welsh

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7 September 2017

4 June 2016

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7 September 2017

Vascular Pharmacology

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7 September 2017

86

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7 September 2017

14-17

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Discovery of vascular permeability factor (VPF).

7 September 2017

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGF receptor protein-tyrosine kinases: structure and regulation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Signal transduction by vascular endothelial growth factor receptors

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Structure of a VEGF-VEGF receptor complex determined by electron microscopy

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Src kinase regulation by phosphorylation and dephosphorylation

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

A Vascular Endothelial Growth Factor Antagonist Is Produced by the Human Placenta and Released into the Maternal Circulation1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Cellular abnormalities of blood vessels as targets in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Vascular endothelial growth factor receptor-1 (VEGFR-1/Flt-1): a dual regulator for angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Vascular endothelial growth factor-B-deficient mice display an atrial conduction defect

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Vascular endothelial growth factor B controls endothelial fatty acid uptake.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

The basis for the distinct biological activities of vascular endothelial growth factor receptor-1 ligands.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGF receptor-2 Y951 signaling and a role for the adapter molecule TSAd in tumor angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Vascular permeability--the essentials

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Essential role of Flk-1 (VEGF receptor 2) tyrosine residue 1173 in vasculogenesis in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Phosphorylation of Tyr1214 within VEGFR-2 triggers the recruitment of Nck and activation of Fyn leading to SAPK2/p38 activation and endothelial cell migration in response to VEGF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGF-A engages at least three tyrosine kinases to activate PI3K/Akt

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGF receptor 2 endocytic trafficking regulates arterial morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Regulation of signaling interactions and receptor endocytosis in growing blood vessels

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Phosphatases and kinases as regulators of the endothelial barrier function

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Lymphangiogenesis: Molecular mechanisms and future promise

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Cardiovascular failure in mouse embryos deficient in VEGF receptor-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Mechanoinduction of lymph vessel expansion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Direct recruitment of CRK and GRB2 to VEGFR-3 induces proliferation, migration, and survival of endothelial cells through the activation of ERK, AKT, and JNK pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

VEGFR3 does not sustain retinal angiogenesis without VEGFR2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

mafba is a downstream transcriptional effector of Vegfc signaling essential for embryonic lymphangiogenesis in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2016.05.011

10.1016/J.VPH.2016.05.011

7 January 2021

Identifiers

DOI

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7 September 2017

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PubMed ID

27268035