Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes (Q38858433)

7 September 2017

Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes (English)

1 reference

7 September 2017

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Eli J Fine

1

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author name string

Caleb M Appleton

2

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7 September 2017

Douglas E White

3

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7 September 2017

Matthew T Brown

4

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7 September 2017

Harshavardhan Deshmukh

5

1 reference

7 September 2017

Melissa L Kemp

6

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7 September 2017

Gang Bao

7

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7 September 2017

language of work or name

English

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publication date

1 July 2015

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7 September 2017

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7 September 2017

5

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7 September 2017

10777

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Creative Commons Attribution 4.0 International

7 September 2017

start time

1 July 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Rational design of a split-Cas9 enzyme complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

SAPTA: a new design tool for improving TALE nuclease activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Genome-scale CRISPR-Cas9 knockout screening in human cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Cas9 as a versatile tool for engineering biology

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

CRISPR RNA-guided activation of endogenous human genes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Optical control of mammalian endogenous transcription and epigenetic states

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

DNA targeting specificity of RNA-guided Cas9 nucleases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Immune responses to AAV vectors: overcoming barriers to successful gene therapy

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Effect of genome size on AAV vector packaging

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Characterization of a naturally occurring trans-splicing intein from Synechocystis sp. PCC6803.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

VMD: visual molecular dynamics

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Protein trans-splicing as a means for viral vector-mediated in vivo gene therapy

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Site-specific chemical modification of proteins with a prelabelled cysteine tag using the artificially split Mxe GyrA intein

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Ligation of a synthetic peptide to the N terminus of a recombinant protein using semisynthetic protein trans-splicing.

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

Engineering artificially split inteins for applications in protein chemistry: biochemical characterization of the split Ssp DnaB intein and comparison to the split Sce VMA intein

22 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4486982

22 August 2018

Identifiers

DOI

10.1038/SREP10777

1 reference

Dimensions Publication ID

7 September 2017

0 references

1 reference

7 September 2017

PubMed publication ID

26126518

1 reference