GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways. (Q38904689)

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English	GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways.	scientific article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25730371%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25730371%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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esophageal squamous cell carcinoma

1 reference

based on heuristic

inferred from title

tumor progression

1 reference

based on heuristic

inferred from title

3

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1 March 2020

Hiroshi Yokozaki

9

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1 March 2020

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Naoki Urakawa

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1 March 2020

Soken Utsunomiya

2

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1 March 2020

Manabu Shigeoka

4

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1 March 2020

Nobuhisa Takase

5

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1 March 2020

Noriaki Arai

6

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1 March 2020

Yoshihiro Kakeji

7

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1 March 2020

Yu-ichiro Koma

8

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1 March 2020

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2 March 2015

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1 March 2020

Laboratory Investigation

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1 March 2020

95

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1 March 2020

5

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1 March 2020

491-503

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1 March 2020

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Ovarian cancer cells polarize macrophages toward a tumor-associated phenotype

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Conventional stents versus stents loaded with (125)iodine seeds for the treatment of unresectable oesophageal cancer: a multicentre, randomised phase 3 trial.

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Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma.

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Tumor associated macrophage expressing CD204 is associated with tumor aggressiveness of esophageal squamous cell carcinoma.

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Tumor-conditioned macrophages secrete migration-stimulating factor: a new marker for M2-polarization, influencing tumor cell motility

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GDF-15 contributes to proliferation and immune escape of malignant gliomas

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Bioactivity and prognostic significance of growth differentiation factor GDF15 secreted by bone marrow mesenchymal stem cells in multiple myeloma.

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Growth differentiation factor 15 stimulates rapamycin-sensitive ovarian cancer cell growth and invasion

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MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

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Molecular cloning and characterization of human nonsteroidal anti-inflammatory drug-activated gene promoter. Basal transcription is mediated by Sp1 and Sp3.

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Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family

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PLAB, a novel placental bone morphogenetic protein

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21 January 2018

Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression

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21 January 2018

GDF15, a cardioprotective TGF-beta superfamily protein

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21 January 2018

Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta

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Growth differentiation factor 15: a prognostic marker for recurrence in colorectal cancer

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Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer

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The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer

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Macrophage infiltration and its prognostic relevance in clear cell renal cell carcinoma.

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Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis

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p53 and NF-κB coregulate proinflammatory gene responses in human macrophages

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Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment

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Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer

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Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy

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21 January 2018

Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma

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21 January 2018

Dysregulated expression of MIC-1/PDF in human prostate tumor cells

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21 January 2018

Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells.

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21 January 2018

Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15.

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Plasma MIC-1 correlates with systemic inflammation but is not an independent determinant of nutritional status or survival in oesophago-gastric cancer

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21 January 2018

Growth differentiation factor 15 is induced by hepatitis C virus infection and regulates hepatocellular carcinoma-related genes

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21 January 2018

Id-1 promotes tumorigenicity and metastasis of human esophageal cancer cells through activation of PI3K/AKT signaling pathway

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MicroRNA-21 promotes the proliferation and inhibits apoptosis in Eca109 via activating ERK1/2/MAPK pathway

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Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system

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https://pubmed.ncbi.nlm.nih.gov/25730371

12 December 2020

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Human peritoneal macrophages show functional characteristics of M-CSF-driven anti-inflammatory type 2 macrophages

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12 December 2020

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Serum markers in patients with resectable pancreatic adenocarcinoma: macrophage inhibitory cytokine 1 versus CA19-9

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12 December 2020

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Esophageal cancer: epidemiology, pathogenesis and prevention

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Growth/differentiation factor-15/macrophage inhibitory cytokine-1 is a novel trophic factor for midbrain dopaminergic neurons in vivo

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12 December 2020

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Tumor-associated macrophages promote invasion while retaining Fc-dependent anti-tumor function.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25730371

12 December 2020

based on heuristic

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