PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation. (Q38909306)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing β-catenin expression and nuclear translocation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

main subject

hepatocellular carcinoma

1 reference

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Y Liu

1

1 reference

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29 February 2020

X Ye

2

1 reference

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29 February 2020

J-B Zhang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

H Ouyang

4

1 reference

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29 February 2020

Z Shen

5

1 reference

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29 February 2020

Y Wu

6

1 reference

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29 February 2020

W Wang

7

1 reference

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29 February 2020

J Wu

8

1 reference

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29 February 2020

S Tao

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

X Yang

10

1 reference

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29 February 2020

K Qiao

11

1 reference

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29 February 2020

J Zhang

12

1 reference

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29 February 2020

J Liu

13

1 reference

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29 February 2020

Y Xie

15

1 reference

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29 February 2020

language of work or name

English

0 references

publication date

16 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

34

1 reference

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29 February 2020

issue

44

1 reference

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29 February 2020

page(s)

5524-5535

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

29 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Sorafenib in advanced hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Wnt signaling in liver cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Mutation and overexpression of the beta-catenin gene may play an important role in primary hepatocellular carcinoma among Chinese people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Tumor suppressor action of liganded thyroid hormone receptor beta by direct repression of beta-catenin gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Zinc finger transcription factor 191, directly binding to β-catenin promoter, promotes cell proliferation of hepatocellular carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

NKX2-5 regulates the expression of beta-catenin and GATA4 in ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Inactivation of PI3K/AKT signaling inhibits glioma cell growth through modulation of β-catenin-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 is an early specific marker for the developing liver and pancreas in the mammalian foregut endoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 regulates the notch1-mediated inhibition of neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 expression patterns in the developing and adult murine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 maintains muscle structure and growth in the developing heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Hepatocyte migration during liver development requires Prox1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Transcription factor PROX1: its role in development and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

PROX1 promotes hepatocellular carcinoma metastasis by way of up-regulating hypoxia-inducible factor 1α expression and protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Prox1 directly interacts with LSD1 and recruits the LSD1/NuRD complex to epigenetically co-repress CYP7A1 transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Wnt signalling and its impact on development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Sorafenib: a clinical and pharmacologic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

Wnt/beta-catenin signaling in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.7

β-catenin plays a key role in metastasis of human hepatocellular carcinoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25684142

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25684142

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2015.7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

29 February 2020

1013922475

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25684142%20AND%20SRC:MED&resulttype=core&format=json