Glutathione, N-acetylcysteine and lipoic acid down-regulate starvation-induced apoptosis, RANKL/OPG ratio and sclerostin in osteocytes: involvement of JNK and ERK1/2 signalling (Q38912068)

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English	Glutathione, N-acetylcysteine and lipoic acid down-regulate starvation-induced apoptosis, RANKL/OPG ratio and sclerostin in osteocytes: involvement of JNK and ERK1/2 signalling	scientific article

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Europe PubMed Central

7 September 2017

Glutathione, N-acetylcysteine and lipoic acid down-regulate starvation-induced apoptosis, RANKL/OPG ratio and sclerostin in osteocytes: involvement of JNK and ERK1/2 signalling (English)

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Europe PubMed Central

7 September 2017

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2 June 2020

Maria Luisa Brandi

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Maria Luisa Brandi

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2 June 2020

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Filippo Fontani

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2 June 2020

Teresa Iantomasi

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2 June 2020

Maria Teresa Vincenzini

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2 June 2020

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10 February 2015

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Calcified Tissue International

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2 June 2020

96

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2 June 2020

335-346

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2 June 2020

https://scigraph.springernature.com/pub.10.1007/s00223-015-9961-0

0 references

Osteocytes, mechanosensing and Wnt signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Local communication on and within bone controls bone remodeling.

1 reference

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The amazing osteocyte

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Osteocyte apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo.

1 reference

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Quantitative regional associations between remodeling, modeling, and osteocyte apoptosis and density in rabbit tibial midshafts

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21 January 2018

Osteocyte: the unrecognized side of bone tissue

1 reference

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21 January 2018

Microdamage and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Osteocyte apoptosis controls activation of intracortical resorption in response to bone fatigue

1 reference

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Osteocyte apoptosis is induced by weightlessness in mice and precedes osteoclast recruitment and bone loss.

1 reference

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21 January 2018

Apoptotic osteocytes regulate osteoclast precursor recruitment and differentiation in vitro

1 reference

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21 January 2018

The role of interstitial fluid flow in the remodeling response to fatigue loading.

1 reference

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21 January 2018

Oxidative stress inhibits osteoblastic differentiation of bone cells by ERK and NF-kappaB.

1 reference

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21 January 2018

Hydrogen peroxide is essential for estrogen-deficiency bone loss and osteoclast formation

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

N-acetylcysteine stimulates osteoblastic differentiation of mouse calvarial cells.

1 reference

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21 January 2018

The antioxidant effect of estrogen and Selective Estrogen Receptor Modulators in the inhibition of osteocyte apoptosis in vitro

1 reference

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21 January 2018

Hydrogen peroxide induces apoptosis of osteocytes: involvement of calcium ion and caspase activity

1 reference

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21 January 2018

Oxidants, oxidative stress and the biology of ageing

1 reference

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21 January 2018

Relationship of age to bone microstructure independent of areal bone mineral density

1 reference

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21 January 2018

Antioxidant status in patients with osteoporosis: a controlled study

1 reference

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21 January 2018

The relation of dietary vitamin C intake to bone mineral density: results from the PEPI study

1 reference

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21 January 2018

Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

The central role of glutathione in the pathophysiology of human diseases

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Alpha-lipoic acid inhibits TNF-alpha-induced apoptosis in human bone marrow stromal cells

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Alpha-lipoic acid suppresses osteoclastogenesis despite increasing the receptor activator of nuclear factor kappaB ligand/osteoprotegerin ratio in human bone marrow stromal cells

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Glutathione dysregulation and the etiology and progression of human diseases.

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Effect of oral ALA supplementation on oxidative stress and insulin sensitivity among overweight/obese adults: a double-blinded, randomized, controlled, cross-over intervention trial

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

RANKL and OPG activity is regulated by injury size in networks of osteocyte-like cells

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Osteocyte-driven bone remodeling

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Reactive oxygen species, cellular redox systems, and apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Glutathione and modulation of cell apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Bisphosphonates and estrogens inhibit osteocyte apoptosis via distinct molecular mechanisms downstream of extracellular signal-regulated kinase activation.

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Pro-survival effects of 17β-estradiol on osteocytes are mediated by nitric oxide/cGMP via differential actions of cGMP-dependent protein kinases I and II

1 reference

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21 January 2018

Fas/CD95 is associated with glucocorticoid-induced osteocyte apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Establishment of an osteocyte-like cell line, MLO-Y4.

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

In vitro and in vivo approaches to study osteocyte biology

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Pro-inflammatory cytokines TNF-related weak inducer of apoptosis (TWEAK) and TNFalpha induce the mitogen-activated protein kinase (MAPK)-dependent expression of sclerostin in human osteoblasts

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Shear stress inhibits while disuse promotes osteocyte apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Gene expression signatures of a fibroblastoid preosteoblast and cuboidal osteoblast cell model compared to the MLO-Y4 osteocyte cell model

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

Osteocyte apoptosis is required for production of osteoclastogenic signals following bone fatigue in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS00223-015-9961-0

21 January 2018

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