An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment (Q38929123)

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scientific article published on 12 December 2014

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English	An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment	scientific article published on 12 December 2014

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

An armed, YB-1-dependent oncolytic adenovirus as a candidate for a combinatorial anti-glioma approach of virotherapy, suicide gene therapy and chemotherapeutic treatment (English)

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

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oncolytic virus

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based on heuristic

inferred from title

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based on heuristic

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based on heuristic

inferred from title

author name string

Y Kostova

1

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Europe PubMed Central

PubMed publication ID

7 September 2017

K Mantwill

2

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Europe PubMed Central

PubMed publication ID

7 September 2017

P S Holm

3

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

M Anton

4

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Europe PubMed Central

PubMed publication ID

7 September 2017

language of work or name

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based on heuristic

inferred from title

publication date

12 December 2014

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Europe PubMed Central

PubMed publication ID

7 September 2017

Cancer Gene Therapy

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Europe PubMed Central

PubMed publication ID

7 September 2017

22

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Europe PubMed Central

PubMed publication ID

7 September 2017

1

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Europe PubMed Central

PubMed publication ID

7 September 2017

30-43

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Europe PubMed Central

PubMed publication ID

7 September 2017

Exciting new advances in neuro-oncology: the avenue to a cure for malignant glioma

1 reference

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Glioblastoma multiforme: a review of where we have been and where we are going

1 reference

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Temozolomide: a review of its discovery, chemical properties, pre-clinical development and clinical trials

1 reference

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

1 reference

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Survival of patients with newly diagnosed glioblastoma treated with radiation and temozolomide in research studies in the United States.

1 reference

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21 January 2018

Prognostic factors for survival in adult patients with recurrent glioma enrolled onto the new approaches to brain tumor therapy CNS consortium phase I and II clinical trials

1 reference

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21 January 2018

Adenovirus-mediated gene therapy with sitimagene ceradenovec followed by intravenous ganciclovir for patients with operable high-grade glioma (ASPECT): a randomised, open-label, phase 3 trial

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Oncolytic virotherapy for malignant glioma: translating laboratory insights into clinical practice

1 reference

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21 January 2018

Tech.Sight. Gene therapy. Hurdles and hopes for cancer treatment

1 reference

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21 January 2018

A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo.

1 reference

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21 January 2018

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

1 reference

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21 January 2018

Evidence that replication of the antitumor adenovirus ONYX-015 is not controlled by the p53 and p14(ARF) tumor suppressor genes.

1 reference

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21 January 2018

Multidrug-resistant cancer cells facilitate E1-independent adenoviral replication: impact for cancer gene therapy

1 reference

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21 January 2018

YB-1: oncoprotein, prognostic marker and therapeutic target?

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

The RNA binding protein YB-1 binds A/C-rich exon enhancers and stimulates splicing of the CD44 alternative exon v4.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

YB-1 promotes strand separation in vitro of duplex DNA containing either mispaired bases or cisplatin modifications, exhibits endonucleolytic activities and binds several DNA repair proteins

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

YB-1 as a Cell Cycle-regulated Transcription Factor Facilitating Cyclin A and Cyclin B1 Gene Expression

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Translational activation of snail1 and other developmentally regulated transcription factors by YB-1 promotes an epithelial-mesenchymal transition

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Direct interaction of p53 with the Y-box binding protein, YB-1: a mechanism for regulation of human gene expression

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Nuclear localization and increased levels of transcription factor YB-1 in primary human breast cancers are associated with intrinsic MDR1 gene expression

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Characterization of the recombinant adenovirus vector AdYB-1: implications for oncolytic vector development

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Novel three-pronged strategy to enhance cancer cell killing in glioblastoma cell lines: histone deacetylase inhibitor, chemotherapy, and oncolytic adenovirus dl520.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Mechanisms of thymidine kinase/ganciclovir and cytosine deaminase/ 5-fluorocytosine suicide gene therapy-induced cell death in glioma cells.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Adenoviral vectors capable of replication improve the efficacy of HSVtk/GCV suicide gene therapy of cancer

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Temozolomide enhances herpes simplex virus thymidine kinase/ganciclovir therapy of malignant glioma.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

A mutant herpes simplex virus type 1 thymidine kinase reporter gene shows improved sensitivity for imaging reporter gene expression with positron emission tomography

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Non-invasive imaging of cardiac transgene expression with PET: comparison of the human sodium/iodide symporter gene and HSV1-tk as the reporter gene

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Deletion of the adenoviral E1b-19kD gene enhances tumor cell killing of a replicating adenoviral vector

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Development and application of quantitative real time PCR and RT-PCR assays that discriminate between the full-length and truncated herpes simplex virus thymidine kinase gene

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Impact of radiation therapy on the oncolytic adenovirus dl520: implications on the treatment of glioblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

The structures of thymidine kinase from herpes simplex virus type 1 in complex with substrates and a substrate analogue

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Characterization of herpes simplex virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Adenovirus E1a protein enhances the cytotoxic effects of the herpes thymidine kinase-ganciclovir system

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Comparison of HSV-1 thymidine kinase-dependent and -independent inhibition of replication-competent adenoviral vectors by a panel of drugs.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Targeted expression of herpes simplex virus thymidine kinase in adenovirus-infected cells reduces virus titers upon treatment with ganciclovir in vitro

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Gap junctions in human glioblastomas: implications for suicide gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

The "bystander effect": association of U-87 cell death with ganciclovir-mediated apoptosis of nearby cells and lack of effect in athymic mice.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Replication-competent, oncolytic herpes simplex virus type 1 mutants induce a bystander effect following ganciclovir treatment

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Cell and environment interactions in tumor microregions: the multicell spheroid model

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Hypoxia reduces adenoviral replication in cancer cells by downregulation of viral protein expression

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Effect of hypoxia on Ad5 infection, transgene expression and replication.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery.

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Herpes simplex virus thymidine kinase/ganciclovir system in multicellular tumor spheroids

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Therapy of head and neck squamous cell carcinoma with an oncolytic adenovirus expressing HSV-tk

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Inclusion of the herpes simplex thymidine kinase gene in a replicating adenovirus does not augment antitumor efficacy

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Utility of TK/GCV in the context of highly effective oncolysis mediated by a serotype 3 receptor targeted oncolytic adenovirus

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

Evaluation of adenoviral oncolytic effect on glioma spheroids by 18F-DG positron-emission tomography

1 reference

https://api.crossref.org/works/10.1038%2FCGT.2014.67

21 January 2018

An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor chemosensitivity conferred by inserted herpes thymidine kinase genes: paradigm for a prospective cancer control strategy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The organotypic multicellular spheroid is a relevant three-dimensional model to study adenovirus replication and penetration in human tumors in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Varicella zoster virus infection of malignant glioma cell cultures: a new candidate for oncolytic virotherapy?

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexpression of herpesviral thymidine kinase reporter gene and VEGF gene for noninvasive monitoring of therapeutic gene transfer: an in vitro evaluation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved median survival for glioblastoma multiforme following introduction of adjuvant temozolomide chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gap junctions play a role in the 'bystander effect' of the herpes simplex virus thymidine kinase/ganciclovir system in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Herpes simplex virus-1 thymidine kinase mutants created by semi-random sequence mutagenesis improve prodrug-mediated tumor cell killing

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the E1B 55 kDa gene product in oncolytic adenoviral vectors expressing herpes simplex virus-tk: assessment of antitumor efficacy and toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the multidrug-resistant phenotype by targeting YB-1 with a conditionally oncolytic adenovirus: implications for combinatorial treatment regimen with chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivation of human neurotropic JC virus expressing oncogenic protein in a recurrent glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy of colon cancer with oncolytic adenovirus is enhanced by the addition of herpes simplex virus-thymidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An adenovirus vector with genetically modified fibers demonstrates expanded tropism via utilization of a coxsackievirus and adenovirus receptor-independent cell entry mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The adenovirus death protein (E3-11.6K) is required at very late stages of infection for efficient cell lysis and release of adenovirus from infected cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A conditionally replicative adenovirus with enhanced infectivity shows improved oncolytic potency.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25501992

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/CGT.2014.67

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

7 September 2017

ResearchGate publication ID

0 references

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