Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer. (Q38931701)

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English	Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer.	scientific article

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24 February 2020

Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer (English)

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24 February 2020

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

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1

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24 February 2020

Dmitri Pchejetski

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24 February 2020

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Qi Wang

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24 February 2020

Adam E Frampton

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24 February 2020

Jonathan Krell

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24 February 2020

Jonathan Waxman

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24 February 2020

Mathias Winkler

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24 February 2020

Justin Stebbing

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24 February 2020

Colin Cooper

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24 February 2020

Ernesto Yagüe

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7 December 2014

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24 February 2020

Breast Cancer Research and Treatment

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24 February 2020

149

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1

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24 February 2020

59-67

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24 February 2020

https://scigraph.springernature.com/pub.10.1007/s10549-014-3228-8

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Global burden of obesity in 2005 and projections to 2030.

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21 January 2018

Minireview: Obesity and breast cancer: the estrogen connection

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21 January 2018

Correlation of body mass index and leptin with tumor size and stage of disease in hormone-dependent postmenopausal breast cancer: preliminary results and therapeutic implications.

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https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Obesity and the risk for premenopausal and postmenopausal breast cancer

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21 January 2018

High expression of leptin receptor mRNA in breast cancer tissue predicts poor prognosis for patients with high, but not low, serum leptin levels

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https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer

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21 January 2018

The ins and outs of leptin receptor activation

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21 January 2018

The multifactorial role of leptin in driving the breast cancer microenvironment.

1 reference

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21 January 2018

Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer

1 reference

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21 January 2018

Activation of the FGFR-STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation.

1 reference

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21 January 2018

A mechanism for epithelial-mesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3).

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https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway

1 reference

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21 January 2018

Therapeutic potential of targeting SK1 in human cancers

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21 January 2018

Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate cancer to docetaxel.

1 reference

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21 January 2018

Identification and expression cloning of a leptin receptor, OB-R

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Leptin enhances growth inhibition by cAMP elevating agents through apoptosis of MDA-MB-231 breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Leptin receptor (OB-R) oligomerizes with itself but not with its closely related cytokine signal transducer gp130.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

STAT3 can be activated through paracrine signaling in breast epithelial cells

1 reference

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21 January 2018

High expression of sphingosine 1-phosphate receptors, S1P1 and S1P3, sphingosine kinase 1, and extracellular signal-regulated kinase-1/2 is associated with development of tamoxifen resistance in estrogen receptor-positive breast cancer patients

1 reference

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21 January 2018

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

1 reference

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21 January 2018

Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.

1 reference

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21 January 2018

leptin-induced growth stimulation of breast cancer cells involves recruitment of histone acetyltransferases and mediator complex to CYCLIN D1 promoter via activation of Stat3

1 reference

https://api.crossref.org/works/10.1007%2FS10549-014-3228-8

21 January 2018

Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

1 reference

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21 January 2018

Interleukin-6 production induced by leptin treatment promotes cell proliferation in an Apc (Min/+) colon epithelial cell line.

1 reference

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21 January 2018

Adipocyte lipolysis-stimulated interleukin-6 production requires sphingosine kinase 1 activity

1 reference

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21 January 2018

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