Lupeol inhibits proliferation and induces apoptosis of human pancreatic cancer PCNA-1 cells through AKT/ERK pathways (Q38938317)

https://doi.org/10.1007/s00210-021-02113-2

7 September 2017

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29 December 2023

title

Lupeol inhibits proliferation and induces apoptosis of human pancreatic cancer PCNA-1 cells through AKT/ERK pathways (English)

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7 September 2017

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Yan Liu

1

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7 September 2017

Tingting Bi

2

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7 September 2017

Gang Wang

3

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7 September 2017

Wei Dai

4

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7 September 2017

Guoliang Wu

5

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7 September 2017

Liqiang Qian

6

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7 September 2017

Quangen Gao

7

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7 September 2017

Genhai Shen

8

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7 September 2017

publication date

25 November 2014

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Naunyn-Schmiedeberg's Archives of Pharmacology

7 September 2017

published in

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7 September 2017

volume

388

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7 September 2017

issue

3

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7 September 2017

page(s)

295-304

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The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention

7 September 2017

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Matrine induces caspase-dependent apoptosis in human osteosarcoma cells in vitro and in vivo through the upregulation of Bax and Fas/FasL and downregulation of Bcl-2.

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PI3-kinase inhibition synergistically promoted the anti-tumor effect of lupeol in hepatocellular carcinoma

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Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors

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Induction of apoptosis by lupeol in human epidermoid carcinoma A431 cells through regulation of mitochondrial, Akt/PKB and NFkappaB signaling pathways

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Lupeol modulates NF-kappaB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice.

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Lupeol inhibits proliferation of human prostate cancer cells by targeting beta-catenin signaling

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Protective effect of lupeol and lupeol linoleate in hypercholesterolemia associated renal damage

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Specific targeting of Wnt/β-catenin signaling in human melanoma cells by a dietary triterpene lupeol

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Downregulation of miR-133 via MAPK/ERK signaling pathway involved in nicotine-induced cardiomyocyte apoptosis

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Antiangiogenic activity of lupeol from Bombax ceiba

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Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling

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Matrine induces apoptosis in human acute myeloid leukemia cells via the mitochondrial pathway and Akt inactivation

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Two triterpenes lupanone and lupeol isolated and identified from Tamarindus indica linn

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12 December 2020

Lupeol supplementation improves blood pressure and lipid metabolism parameters in stroke-prone spontaneously hypertensive rats

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12 December 2020

Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosis

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12 December 2020

The expression and clinical significance of PI3K, pAkt and VEGF in colon cancer

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12 December 2020

Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting

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12 December 2020

Lupeol induces apoptosis and inhibits invasion in gallbladder carcinoma GBC-SD cells by suppression of EGFR/MMP-9 signaling pathway

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12 December 2020

Oxymatrine triggers apoptosis by regulating Bcl-2 family proteins and activating caspase-3/caspase-9 pathway in human leukemia HL-60 cells

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12 December 2020

10.1007/S00210-014-1071-4

Identifiers

DOI

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Dimensions Publication ID

7 September 2017

1048032771

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