Conformational evaluation of HIV-1 trimeric envelope glycoproteins using a cell-based ELISA assay. (Q38950236)

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20 February 2020

title

Conformational evaluation of HIV-1 trimeric envelope glycoproteins using a cell-based ELISA assay (English)

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20 February 2020

7

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20 February 2020

6

Michel Roger

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20 February 2020

author name string

Maxime Veillette

1

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20 February 2020

Mathieu Coutu

2

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20 February 2020

Jonathan Richard

3

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20 February 2020

Laurie-Anne Batraville

4

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20 February 2020

Anik Désormeaux

5

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20 February 2020

publication date

14 September 2014

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Journal of Visualized Experiments

20 February 2020

published in

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issue

91

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20 February 2020

page(s)

51995

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Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicity

20 February 2020

cites work

1 reference

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Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation

9 September 2017

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9 September 2017

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9 September 2017

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The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.

9 September 2017

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Proteolytic processing of the human immunodeficiency virus envelope glycoprotein precursor decreases conformational flexibility

9 September 2017

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9 September 2017

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Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family

9 September 2017

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HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.

9 September 2017

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HIV vaccine development: challenges and opportunities towards solving the HIV vaccine-neutralizing antibody problem

9 September 2017

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Broad neutralization coverage of HIV by multiple highly potent antibodies

9 September 2017

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Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity.

9 September 2017

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Topological layers in the HIV-1 gp120 inner domain regulate gp41 interaction and CD4-triggered conformational transitions

9 September 2017

1 reference

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Structural Basis of Immune Evasion at the Site of CD4 Attachment on HIV-1 gp120

9 September 2017

1 reference

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Vaccination with ALVAC and AIDSVAX to prevent HIV-1 infection in Thailand

9 September 2017

1 reference

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Transitions to and from the CD4-bound conformation are modulated by a single-residue change in the human immunodeficiency virus type 1 gp120 inner domain

9 September 2017

1 reference

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Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state

9 September 2017

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HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

9 September 2017

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Mutagenic stabilization and/or disruption of a CD4-bound state reveals distinct conformations of the human immunodeficiency virus type 1 gp120 envelope glycoprotein

9 September 2017

1 reference

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Determinants of human immunodeficiency virus type 1 entry in the CDR2 loop of the CD4 glycoprotein.

9 September 2017

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Immunological evidence for interactions between the first, second, and fifth conserved domains of the gp120 surface glycoprotein of human immunodeficiency virus type 1.

9 September 2017

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Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding

9 September 2017

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Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160.

9 September 2017

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Model for intracellular folding of the human immunodeficiency virus type 1 gp120

9 September 2017

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Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cells

9 September 2017

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Mutational analysis of the human immunodeficiency virus type 1 env gene product proteolytic cleavage site

9 September 2017

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Human immunodeficiency virus type 1 gp120 envelope glycoprotein regions important for association with the gp41 transmembrane glycoprotein

9 September 2017

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Effects of changes in gp120-CD4 binding affinity on human immunodeficiency virus type 1 envelope glycoprotein function and soluble CD4 sensitivity

9 September 2017

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9 September 2017

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Immunization with recombinant canarypox vectors expressing membrane-anchored glycoprotein 120 followed by glycoprotein 160 boosting fails to generate antibodies that neutralize R5 primary isolates of human immunodeficiency virus type 1.

9 September 2017

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Characterization of the multiple conformational States of free monomeric and trimeric human immunodeficiency virus envelope glycoproteins after fixation by cross-linker

25 September 2017

1 reference

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Immunization with envelope subunit vaccine products elicits neutralizing antibodies against laboratory-adapted but not primary isolates of human immunodeficiency virus type 1. The National Institute of Allergy and Infectious Diseases AIDS Vaccine Ev

17 June 2018

1 reference

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Toward an effective AIDS vaccine development.

17 June 2018

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The HIV-1 Env Protein Signal Sequence Retards Its Cleavage and Down-regulates the Glycoprotein Folding

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25286159

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3791/51995

1 reference

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20 February 2020

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20 February 2020

PubMed publication ID

25286159

1 reference

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