Ectromelia virus encodes a family of Ankyrin/F-box proteins that regulate NFκB. (Q38954768)

7 September 2017

Ectromelia virus encodes a family of Ankyrin/F-box proteins that regulate NFκB. (English)

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7 September 2017

Ectromelia virus

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Kristin Burles

1

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7 September 2017

Nicholas van Buuren

series ordinal

2

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7 September 2017

Michele Barry

series ordinal

3

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7 September 2017

language of work or name

English

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publication date

18 September 2014

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7 September 2017

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7 September 2017

468-470

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7 September 2017

351-362

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Comparison of the Antiviral Effects of 5-Methoxymethyl-deoxyuridine with 5-Iododeoxyuridine, Cytosine Arabinoside, and Adenine Arabinoside

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The human immunodeficiency virus type 1 Vpu protein inhibits NF-kappa B activation by interfering with beta TrCP-mediated degradation of Ikappa B.

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A46R and A52R from vaccinia virus are antagonists of host IL-1 and toll-like receptor signaling.

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Innate immune activation of NFκB and its antagonism by poxviruses

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Initial characterization of vaccinia virus B4 suggests a role in virus spread

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The SCF ubiquitin ligase: insights into a molecular machine

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Identification of a family of human F-box proteins

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Vaccinia virus strain Western Reserve protein B14 is an intracellular virulence factor

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Inhibition of IkappaB kinase by vaccinia virus virulence factor B14

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Antiviral activity of O'-alkylated derivatives of cytosine arabinoside

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Poxvirus protein N1L targets the I-kappaB kinase complex, inhibits signaling to NF-kappaB by the tumor necrosis factor superfamily of receptors, and inhibits NF-kappaB and IRF3 signaling by toll-like receptors

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A vaccinia virus deletion mutant reveals the presence of additional inhibitors of NF-kappaB.

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Vaccinia virus-encoded ribonucleotide reductase subunits are differentially required for replication and pathogenesis

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Poxviral regulation of the host NF-kappaB response: the vaccinia virus M2L protein inhibits induction of NF-kappaB activation via an ERK2 pathway in virus-infected human embryonic kidney cells.

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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism

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Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

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The poxvirus protein A52R targets Toll-like receptor signaling complexes to suppress host defense

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Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

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Shared principles in NF-kappaB signaling

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NF-κB, the first quarter-century: remarkable progress and outstanding questions

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Characterization of wild-type and mutant vaccinia virus M2L proteins' abilities to localize to the endoplasmic reticulum and to inhibit NF-kappaB activation during infection

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Hostile takeovers: viral appropriation of the NF-kB pathway

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Manipulation of the nuclear factor-kappaB pathway and the innate immune response by viruses

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Genetic analysis of NF- B/Rel transcription factors defines functional specificities

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Poxvirus immunomodulatory strategies: current perspectives

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HSV-1 ICP27 suppresses NF-kappaB activity by stabilizing IkappaBalpha

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The F-box protein family.

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Inducible degradation of IkappaBalpha by the proteasome requires interaction with the F-box protein h-betaTrCP.

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Regulation of NF-kappaB inhibitor IkappaBalpha and viral replication by a KSHV microRNA

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Ankyrin repeat: a unique motif mediating protein-protein interactions.

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Vaccinia virus expresses a novel profilin with a higher affinity for polyphosphoinositides than actin

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Poxvirus targeting of E3 ligase β-TrCP by molecular mimicry: a mechanism to inhibit NF-κB activation and promote immune evasion and virulence

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F-box-like domains are present in most poxvirus ankyrin repeat proteins

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NFkB inhibitors: strategies from poxviruses

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Immunology 101 at poxvirus U: immune evasion genes

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Vaccinia virus E3 suppresses expression of diverse cytokines through inhibition of the PKR, NF-kappaB, and IRF3 pathways

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Function and regulation of cullin-RING ubiquitin ligases

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Modulation of NF-κB signalling by microbial pathogens

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Crosstalk between the type 1 interferon and nuclear factor kappa B pathways confers resistance to a lethal virus infection.

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Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90.

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Viral targeting of DEAD box protein 3 reveals its role in TBK1/IKKepsilon-mediated IRF activation

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Poxviruses and immune evasion

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The vaccinia virus K1L gene product inhibits host NF-kappaB activation by preventing IkappaBalpha degradation

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Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

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Nucleotide sequence of 42 kbp of vaccinia virus strain WR from near the right inverted terminal repeat

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Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes

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Vaccinia virus encodes I5, a small hydrophobic virion membrane protein that enhances replication and virulence in mice

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Signal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCP

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Vaccinia virus protein A46R targets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence

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Mechanism of inactivation of NF-kappa B by a viral homologue of I kappa b alpha. Signal-induced release of i kappa b alpha results in binding of the viral homologue to NF-kappa B.

7 January 2021

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A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

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Regulation and function of NF-kappaB transcription factors in the immune system

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EVM005: an ectromelia-encoded protein with dual roles in NF-κB inhibition and virulence

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Ectromelia virus encodes a novel family of F-box proteins that interact with the SCF complex

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Functional and evolutionary insights from the genomes of three parasitoid Nasonia species

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Ubiquitin-mediated regulation of TNFR1 signaling

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Ectromelia virus BTB/kelch proteins, EVM150 and EVM167, interact with cullin-3-based ubiquitin ligases

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Viral protease cleavage of inhibitor of kappaBalpha triggers host cell apoptosis

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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

7 January 2021

1 reference

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10.1016/J.VIROL.2014.08.030

7 January 2021

Identifiers

DOI

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7 September 2017

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