Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer. (Q38965991)

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12 March 2020

title

Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer (English)

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12 March 2020

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8

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12 March 2020

Hippokratis Kiaris

11

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Ioannis Karavokyros

13

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17

Efthimia K Basdra

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12 March 2020

author name string

Antonios N Gargalionis

1

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12 March 2020

Penelope Korkolopoulou

2

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Elena Farmaki

3

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12 March 2020

Christina Piperi

4

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12 March 2020

Georgia Dalagiorgou

5

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12 March 2020

Christos Adamopoulos

6

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Georgia Levidou

7

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Paraskevi Fragkou

9

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Panagiota Tsioli

10

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Adamantia Zizi-Serbetzoglou

12

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Kostas A Papavassiliou

14

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Nikolaos Tsavaris

15

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Efstratios Patsouris

16

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12 March 2020

Athanasios G Papavassiliou

18

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language of work or name

English

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publication date

3 September 2014

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International Journal of Cancer

12 March 2020

published in

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volume

136

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issue

7

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12 March 2020

page(s)

1515-1527

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What does physics have to do with cancer?

12 March 2020

cites work

1 reference

The physics of cancer: the role of physical interactions and mechanical forces in metastasis

21 January 2018

1 reference

Polycystins and partners: proposed role in mechanosensitivity.

21 January 2018

1 reference

Transmembrane Domain Analysis of Polycystin-1, the Product of the Polycystic Kidney Disease-1 (PKD1) Gene: Evidence for 11 Membrane-Spanning Domains

21 January 2018

1 reference

Polycystin-1: function as a mechanosensor

21 January 2018

1 reference

The polycystic kidney disease-1 protein, polycystin-1, binds and activates heterotrimeric G-proteins in vitro.

21 January 2018

1 reference

The human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-termini

21 January 2018

1 reference

Subcellular localization and trafficking of polycystins

21 January 2018

1 reference

Distinct subcellular expression of endogenous polycystin-2 in the plasma membrane and Golgi apparatus of MDCK cells

21 January 2018

1 reference

Polycystin-2 is an intracellular calcium release channel

21 January 2018

1 reference

Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents

21 January 2018

1 reference

The polycystic kidney disease proteins, polycystin-1, polycystin-2, polaris, and cystin, are co-localized in renal cilia

21 January 2018

1 reference

Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells

21 January 2018

1 reference

Endothelial cilia are fluid shear sensors that regulate calcium signaling and nitric oxide production through polycystin-1

21 January 2018

1 reference

mTOR signaling in polycystic kidney disease

21 January 2018

1 reference

Polycystins and primary cilia: primers for cell cycle progression

21 January 2018

1 reference

Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

21 January 2018

1 reference

ERp29 regulates response to doxorubicin by a PERK-mediated mechanism

21 January 2018

1 reference

Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis

21 January 2018

1 reference

Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells

21 January 2018

1 reference

Microsatellite instability in colorectal cancer

21 January 2018

1 reference

A comprehensive immunohistochemical and molecular approach to the PI3K/AKT/mTOR (phosphoinositide 3-kinase/v-akt murine thymoma viral oncogene/mammalian target of rapamycin) pathway in bladder urothelial carcinoma.

21 January 2018

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Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells

21 January 2018

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Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer.

21 January 2018

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Role of histone lysine methyltransferases SUV39H1 and SETDB1 in gliomagenesis: modulation of cell proliferation, migration, and colony formation

21 January 2018

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TGF-beta signalling in colon carcinogenesis

21 January 2018

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Prognostic significance of transforming growth factor beta (TGF-β) signaling axis molecules and E-cadherin in colorectal cancer.

21 January 2018

1 reference

FAK, CD44v6, c-Met and EGFR in colorectal cancer parameters: tumour progression, metastasis, patient survival and receptor crosstalk

21 January 2018

1 reference

Vascular endothelial growth factor receptors 1,3 and caveolin-1 are implicated in colorectal cancer aggressiveness and prognosis--correlations with epidermal growth factor receptor, CD44v6, focal adhesion kinase, and c-Met

21 January 2018

1 reference

The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction.

21 January 2018

1 reference

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

Epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions in the colon

21 January 2018

1 reference

Polycystins, focal adhesions and extracellular matrix interactions

21 January 2018

1 reference

The cell biology of polycystic kidney disease

21 January 2018

1 reference

The translational landscape of mTOR signalling steers cancer initiation and metastasis

21 January 2018

1 reference

mTOR signaling in cancer cell motility and tumor metastasis

21 January 2018

1 reference

mTORC1 and mTORC2 regulate EMT, motility, and metastasis of colorectal cancer via RhoA and Rac1 signaling pathways

21 January 2018

1 reference

Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.

21 January 2018

1 reference

Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.

21 January 2018

1 reference

The clinicopathological features of colorectal mucinous adenocarcinoma and a therapeutic strategy for the disease

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.29140

1 reference

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12 March 2020

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