DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease (Q38972171)

8 September 2017

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease (English)

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8 September 2017

1 reference

1

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13 June 2020

Leonor Miller-Fleming

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13 June 2020

Mariaelena Repici

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13 June 2020

Sandra Tenreiro

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13 June 2020

Rita Rosado-Ramos

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13 June 2020

Kornelis Straatman

8

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13 June 2020

Poul Henning Jensen

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13 June 2020

Tiago Fleming Outeiro

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author name string

S Gonçalves

4

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13 June 2020

C Betzer

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13 June 2020

F Giorgini

10

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13 June 2020

publication date

24 July 2014

1 reference

8 September 2017

Cell Death and Disease

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13 June 2020

volume

5

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13 June 2020

page(s)

e1350

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Creative Commons Attribution 3.0 Unported

13 June 2020

copyright license

start time

1 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4123098/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/cddis.2014.307

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cites work

DJ-1 is a copper chaperone acting on SOD1 activation

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9 September 2017

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Parkinson's disease-associated DJ-1 mutations impair mitochondrial dynamics and cause mitochondrial dysfunction

9 September 2017

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Accumulation of toxic α-synuclein oligomer within endoplasmic reticulum occurs in α-synucleinopathy in vivo.

9 September 2017

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Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy

9 September 2017

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Pathological roles of α-synuclein in neurological disorders

9 September 2017

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Direct membrane association drives mitochondrial fission by the Parkinson disease-associated protein alpha-synuclein

9 September 2017

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L10p and P158DEL DJ-1 mutations cause protein instability, aggregation, and dimerization impairments

9 September 2017

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Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics

9 September 2017

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Zooming into protein oligomerization in neurodegeneration using BiFC.

9 September 2017

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Oligomeric alpha-synuclein and its role in neuronal death

9 September 2017

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DJ-1, PINK1, and their effects on mitochondrial pathways

9 September 2017

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DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.

9 September 2017

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Alpha-synuclein and Parkinson's disease: a proteomic view

9 September 2017

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Structural effects of Parkinson's disease linked DJ-1 mutations.

9 September 2017

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Formation of toxic oligomeric alpha-synuclein species in living cells

9 September 2017

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9 September 2017

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The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis

9 September 2017

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9 September 2017

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Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models

9 September 2017

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9 September 2017

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9 September 2017

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DJ-1 up-regulates glutathione synthesis during oxidative stress and inhibits A53T alpha-synuclein toxicity

9 September 2017

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9 September 2017

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DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation

9 September 2017

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Lewy-body formation is an aggresome-related process: a hypothesis

9 September 2017

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The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization

9 September 2017

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The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: A member of the DJ-1/ThiJ/PfpI superfamily

9 September 2017

1 reference

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The 1.1-A resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

9 September 2017

1 reference

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The crystal structure of DJ-1, a protein related to male fertility and Parkinson's disease

9 September 2017

1 reference

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Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis

9 September 2017

1 reference

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Park7, a novel locus for autosomal recessive early-onset parkinsonism, on chromosome 1p36.

9 September 2017

1 reference

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Microtubule-associated protein 1B is a component of cortical Lewy bodies and binds alpha-synuclein filaments

9 September 2017

1 reference

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Alpha-synuclein in Lewy bodies

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

PLK2 modulates α-synuclein aggregation in yeast and mammalian cells

9 September 2017

1 reference

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Phenylbutyrate up-regulates the DJ-1 protein and protects neurons in cell culture and in animal models of Parkinson disease

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

DJ-1 decreases Bax expression through repressing p53 transcriptional activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Aggregation and neurotoxicity of recombinant α-synuclein aggregates initiated by dimerization

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Characterizing the dynamics of α-synuclein oligomers using hydrogen/deuterium exchange monitored by mass spectrometry

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Toxic prefibrillar α-synuclein amyloid oligomers adopt a distinctive antiparallel β-sheet structure.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Interaction between α-synuclein and other proteins in neurodegenerative disorders.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

Yeast cells provide insight into alpha-synuclein biology and pathobiology

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4123098

-Synuclein and Parkinson disease susceptibility

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2014.307

DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism

21 January 2018

1 reference

12 December 2020

Small-scale density gradient sedimentation to separate and analyze multiprotein complexes

1 reference

12 December 2020

Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1

1 reference

12 December 2020

DJ-1 forms complexes with mutant SOD1 and ameliorates its toxicity

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDDIS.2014.307

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25058424%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25058424%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

PubMed publication ID

25058424

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25058424%20AND%20SRC:MED&resulttype=core&format=json