Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα. (Q38982861)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947179%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

title

Loss of histone demethylase KDM6B enhances aggressiveness of pancreatic cancer through downregulation of C/EBPα (English)

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20 March 2020

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11

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17

Norihiro Kokudo

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19

Kazuhiko Koike

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20 March 2020

author name string

Keisuke Yamamoto

1

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20 March 2020

Keisuke Tateishi

2

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20 March 2020

Yotaro Kudo

3

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Tomohiko Sato

4

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Shinzo Yamamoto

5

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Koji Miyabayashi

6

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20 March 2020

Keisuke Matsusaka

7

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20 March 2020

Yoshinari Asaoka

8

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20 March 2020

Hideaki Ijichi

9

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20 March 2020

Yoshihiro Hirata

10

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20 March 2020

Yousuke Nakai

12

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Hiroyuki Isayama

13

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20 March 2020

Tsuneo Ikenoue

14

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20 March 2020

Mineo Kurokawa

15

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20 March 2020

Masashi Fukayama

16

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20 March 2020

Masao Omata

18

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language of work or name

English

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publication date

19 June 2014

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20 March 2020

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20 March 2020

volume

35

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20 March 2020

issue

11

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20 March 2020

page(s)

2404-2414

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20 March 2020

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

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Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

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Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

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Chromatin modifications and their function

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Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

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Insights into the epigenetic mechanisms controlling pancreatic carcinogenesis

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Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma

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Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

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EZH2 couples pancreatic regeneration to neoplastic progression

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Control of developmental regulators by Polycomb in human embryonic stem cells

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Deregulation of H3K27 methylation in cancer

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Regulation of pancreatic tumor cell proliferation and chemoresistance by the histone methyltransferase enhancer of zeste homologue 2.

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UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

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The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence

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Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS

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JMJD3 is a histone H3K27 demethylase.

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The H3K27me3 demethylase, KDM6B, is induced by Epstein-Barr virus and over-expressed in Hodgkin's Lymphoma

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Histone demethylase KDM6B promotes epithelial-mesenchymal transition

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Expression and significance of histone H3K27 demethylases in renal cell carcinoma

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Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes

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Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease

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Mutations in the p53 gene occur in diverse human tumour types

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Integrated analysis of copy number alterations and loss of heterozygosity in human pancreatic cancer using a high-resolution, single nucleotide polymorphism array

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Histone demethylase KDM4C regulates sphere formation by mediating the cross talk between Wnt and Notch pathways in colonic cancer cells.

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Identifiers

DOI

10.1093/CARCIN/BGU136

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24947179%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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