Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma. (Q39004271)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732040%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

title

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma (English)

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14 March 2020

0 references

1

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14 March 2020

Marina Martello

4

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14 March 2020

Gianandrea Pasquinelli

9

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14 March 2020

author name string

Giulia Perrone

2

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14 March 2020

Carolina Terragna

3

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14 March 2020

Angela F Dico

5

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14 March 2020

Giancarlo Solaini

6

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14 March 2020

Alessandra Baracca

7

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14 March 2020

Gianluca Sgarbi

8

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14 March 2020

Sabrina Valente

10

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14 March 2020

Elena Zamagni

11

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14 March 2020

Paola Tacchetti

12

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14 March 2020

Michele Cavo

14

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14 March 2020

Giovanni Martinelli

13

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14 March 2020

language of work or name

English

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publication date

1 April 2014

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14 March 2020

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14 March 2020

volume

5

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14 March 2020

page(s)

1779-1792

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14 March 2020

issue

7

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Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology

14 March 2020

cites work

1 reference

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9 September 2017

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9 September 2017

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9 September 2017

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9 September 2017

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HIF gene expression in cancer therapy

9 September 2017

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9 September 2017

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9 September 2017

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Hypoxia-inducible factor 1 and dysregulated c-Myc cooperatively induce vascular endothelial growth factor and metabolic switches hexokinase 2 and pyruvate dehydrogenase kinase 1

9 September 2017

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Evaluating mitochondrial membrane potential in cells

9 September 2017

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Hypoxia and adaptive landscapes in the evolution of carcinogenesis

9 September 2017

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Hypoxia-inducible factor-1alpha expression in the gastric carcinogenesis sequence and its prognostic role in gastric and gastro-oesophageal adenocarcinomas

9 September 2017

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Cancer's molecular sweet tooth and the Warburg effect.

9 September 2017

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The role of hypoxia-induced factors in tumor progression

9 September 2017

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

9 September 2017

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Protein measurement with the Folin phenol reagent

9 September 2017

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On respiratory impairment in cancer cells

9 September 2017

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On the Origin of Cancer Cells

9 September 2017

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Cyclin E induction by genotoxic stress leads to apoptosis of hematopoietic cells

9 September 2017

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A link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.

9 September 2017

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

9 September 2017

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Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

9 September 2017

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Cell cycle checkpoints: preventing an identity crisis

9 September 2017

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DNA binding and transcriptional properties of wild-type and mutant forms of the homeodomain protein Msx2

9 September 2017

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Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

9 September 2017

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Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.

9 September 2017

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PDK1 inhibition is a novel therapeutic target in multiple myeloma

9 September 2017

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Inhibition of hypoxia-inducible factor-1 function enhances the sensitivity of multiple myeloma cells to melphalan

9 September 2017

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Targeting angiogenesis via a c-Myc/hypoxia-inducible factor-1alpha-dependent pathway in multiple myeloma

14 September 2017

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A RNA antagonist of hypoxia-inducible factor-1alpha, EZN-2968, inhibits tumor cell growth

14 September 2017

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The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angio

14 September 2017

1 reference

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Effects of ras and von Hippel-Lindau (VHL) gene mutations on hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha, and vascular endothelial growth factor expression and their regulation by the phosphatidylinositol 3'-kinase/Akt signaling pathway

14 September 2017

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Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

25 September 2017

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Inefficient coupling between proton transport and ATP synthesis may be the pathogenic mechanism for NARP and Leigh syndrome resulting from the T8993G mutation in mtDNA.

25 September 2017

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Glucose plays a main role in human fibroblasts adaptation to hypoxia

17 June 2018

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Targeting the multiple myeloma hypoxic niche with TH-302, a hypoxia-activated prodrug

21 August 2018

1 reference

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Hypoxia-inducible factor-1alpha is a key regulator of metastasis in a transgenic model of cancer initiation and progression.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4039126

Role of the hypoxic bone marrow microenvironment in 5T2MM murine myeloma tumor progression.

21 August 2018

1 reference

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Hypoxia-inducible factor 1 alpha expression correlates with angiogenesis and unfavorable prognosis in bladder cancer.

21 August 2018

1 reference

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Activation of the transcription factor HIF-1 and its target genes, VEGF, HO-1, iNOS, during fracture repair.

21 August 2018

1 reference

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The relation between hypoxia-inducible factor (HIF)-1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer

21 August 2018

1 reference

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Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer

2 December 2018

1 reference

12 December 2020

Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer

1 reference

12 December 2020

HIF hits Wnt in the stem cell niche

1 reference

12 December 2020

Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138+ cells

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.1736

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732040%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732040%20AND%20SRC:MED&resulttype=core&format=json

14 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24732040%20AND%20SRC:MED&resulttype=core&format=json