FGFR-TACC gene fusions in human glioma (Q39010445)

http://europepmc.org/abstract/PMC/5464372

17 June 2018

review article

1 reference

title

FGFR-TACC gene fusions in human glioma (English)

1 reference

http://europepmc.org/abstract/PMC/5464372

17 June 2018

author

Anna Lasorella

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Antonio Iavarone

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Marc Sanson

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

publication date

1 April 2017

1 reference

http://europepmc.org/abstract/PMC/5464372

17 June 2018

published in

Neuro-Oncology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

475-483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

Clonal evolution of glioblastoma under therapy.

5 June 2020

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Oncogenic Gene Fusion FGFR3-TACC3 Is Regulated by Tyrosine Phosphorylation

22 June 2018

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Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma.

22 June 2018

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Recurrent FGFR3-TACC3 fusion gene in nasopharyngeal carcinoma

22 June 2018

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The landscape and therapeutic relevance of cancer-associated transcript fusions.

22 June 2018

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Molecular and cellular heterogeneity: the hallmark of glioblastoma

22 June 2018

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The landscape of kinase fusions in cancer

22 June 2018

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Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

22 June 2018

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Integrated genomic characterization reveals novel, therapeutically relevant drug targets in FGFR and EGFR pathways in sporadic intrahepatic cholangiocarcinoma

22 June 2018

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Novel treatment of acute promyelocytic leukemia: As₂O₃, retinoic acid and retinoid pharmacology

22 June 2018

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Deep molecular response in chronic myeloid leukemia: the new goal of therapy?

22 June 2018

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Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma

22 June 2018

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Parallel RNA interference screens identify EGFR activation as an escape mechanism in FGFR3-mutant cancer

22 June 2018

1 reference

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Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.

22 June 2018

1 reference

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Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464372

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas

22 June 2018

1 reference

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Identification of targetable FGFR gene fusions in diverse cancers.

22 June 2018

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Fibroblast growth factor receptor inhibitors as a cancer treatment: from a biologic rationale to medical perspectives

22 June 2018

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Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics.

22 June 2018

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The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma

22 June 2018

1 reference

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Oncogenic FGFR3 gene fusions in bladder cancer

22 June 2018

1 reference

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Rescue screens with secreted proteins reveal compensatory potential of receptor tyrosine kinases in driving cancer growth

22 June 2018

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Transforming fusions of FGFR and TACC genes in human glioblastoma

22 June 2018

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22 June 2018

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Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

22 June 2018

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Discovery of 3-(2,6-dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), a potent and selective inhibitor of the fibroblast growth factor receptor family of receptor tyrosine kinase

22 June 2018

1 reference

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Pulling it together: The mitotic function of TACC3.

22 June 2018

1 reference

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Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

22 June 2018

1 reference

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ALK-targeted therapy for lung cancer: ready for prime time.

22 June 2018

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ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time

22 June 2018

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Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-targeted genes

22 June 2018

1 reference

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Residual tumor cells are unique cellular targets in glioblastoma

22 June 2018

1 reference

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Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy

22 June 2018

1 reference

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Fibroblast growth factor signalling: from development to cancer

22 June 2018

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Complex landscapes of somatic rearrangement in human breast cancer genomes

22 June 2018

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Oncogenic gene fusions in epithelial carcinomas

22 June 2018

1 reference

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The TACC proteins: TACC-ling microtubule dynamics and centrosome function

22 June 2018

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22 June 2018

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The development of phase I cancer trial methodologies: the use of pharmacokinetic and pharmacodynamic end points sets the scene for phase 0 cancer clinical trials

22 June 2018

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Aneuploidy: cells losing their balance

22 June 2018

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Phase 0 clinical trials: conceptions and misconceptions

22 June 2018

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EML4-ALK fusion lung cancer: a rare acquired event

22 June 2018

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The impact of translocations and gene fusions on cancer causation

22 June 2018

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22 June 2018

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Cellular signaling by fibroblast growth factor receptors

22 June 2018

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The docking protein FRS2alpha controls a MAP kinase-mediated negative feedback mechanism for signaling by FGF receptors

22 June 2018

1 reference

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Critical role for the docking-protein FRS2 alpha in FGF receptor-mediated signal transduction pathways

22 June 2018

1 reference

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The third member of the transforming acidic coiled coil-containing gene family, TACC3, maps in 4p16, close to translocation breakpoints in multiple myeloma, and is upregulated in various cancer cell lines

22 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464372

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

22 June 2018

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Phase I Dose-Escalation Study of JNJ-42756493, an Oral Pan-Fibroblast Growth Factor Receptor Inhibitor, in Patients With Advanced Solid Tumors

22 June 2018

1 reference

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Identification of recurrent FGFR3-TACC3 fusion oncogenes from lung adenocarcinoma

21 August 2018

1 reference

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FGFR1/3 tyrosine kinase fusions define a unique molecular subtype of non-small cell lung cancer

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464372

Whole-genome and whole-exome sequencing of bladder cancer identifies frequent alterations in genes involved in sister chromatid cohesion and segregation

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464372

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5464372

Disruption of Tacc3 function leads to in vivo tumor regression.

21 August 2018

1 reference

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Compressing drug development timelines in oncology using phase '0' trials.

21 August 2018

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Management of intracranial aneurysms associated with arteriovenous malformations

21 August 2018

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Crossref

https://api.crossref.org/works/10.1093%2FNEUONC%2FNOW240

21 January 2018

Identifiers

DOI

10.1093/NEUONC/NOW240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27852792%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference