The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function. (Q39012184)

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scientific article published on 19 June 2014

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English	The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function.	scientific article published on 19 June 2014

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Retraction Watch

29 December 2023

https://doi.org/10.1186/s10020-020-00265-0

http://retractionwatch.com/?s=Daniel+J+Antoine

The α7 nicotinic acetylcholine receptor agonist GTS-21 improves bacterial clearance in mice by restoring hyperoxia-compromised macrophage function (English)

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Ravikumar A Sitapara

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Daniel J Antoine

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Charles R Ashby

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Samir Gorasiya

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Huan Yang

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Michelle Zur

8

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Lin L Mantell

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19 June 2014

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Molecular Medicine

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238-247

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1 January 2014

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Inhibition of extracellular HMGB1 attenuates hyperoxia-induced inflammatory acute lung injury

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High Mobility Group Box-1 mediates hyperoxia-induced impairment of Pseudomonas aeruginosa clearance and inflammatory lung injury in mice

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Lipopolysaccharide upregulates α7 acetylcholine receptors: stimulation with GTS-21 mitigates growth arrest of macrophages and improves survival in burned mice

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High mobility group protein-1 inhibits phagocytosis of apoptotic neutrophils through binding to phosphatidylserine

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Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia

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Ventilator-associated pneumonia: a review

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Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

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HMG-1 rediscovered as a cytokine

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High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

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LPS induces HMGB1 relocation and release by activating the NF-κB-CBP signal transduction pathway in the murine macrophage-like cell line RAW264.7.

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Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis

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Activation of gene expression in human neutrophils by high mobility group box 1 protein

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Impairment of phagocytosis by moderate hyperoxia (40 to 60 per cent oxygen) in lung macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/24664237

12 December 2020

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10.2119/MOLMED.2013.00086

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9 September 2019

https://scigraph.springernature.com/pub.10.2119/molmed.2013.00086

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Europe PubMed Central

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12 March 2020

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Europe PubMed Central

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12 March 2020

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