MIF4G domain containing protein regulates cell cycle and hepatic carcinogenesis by antagonizing CDK2-dependent p27 stability. (Q39043607)

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3 March 2020

title

MIF4G domain containing protein regulates cell cycle and hepatic carcinogenesis by antagonizing CDK2-dependent p27 stability (English)

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3 March 2020

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C Wan

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S Hou

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L Lv

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Z Ding

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X Huang

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Q Hang

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S He

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Y Wang

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C Cheng

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X X Gu

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G Xu

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language of work or name

English

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publication date

16 December 2013

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3 March 2020

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3 March 2020

volume

34

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issue

2

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page(s)

237-245

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The global burden of cancer: priorities for prevention

3 March 2020

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Cell-free degradation of p27(kip1), a G1 cyclin-dependent kinase inhibitor, is dependent on CDK2 activity and the proteasome

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Upregulation of p27 and its inhibition of CDK2/cyclin E activity following DNA damage by a novel platinum agent are dependent on the expression of p21

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Expression and altered subcellular localization of the cyclin-dependent kinase inhibitor p27Kip1 in hepatocellular carcinoma

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Expression of Pirh2, a p27(Kip1) ubiquitin ligase, in hepatocellular carcinoma: correlation with p27(Kip1) and cell proliferation.

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Early mitotic inhibitor-1, an anaphase-promoting complex/cyclosome inhibitor, can control tumor cell proliferation in hepatocellular carcinoma: correlation with Skp2 stability and degradation of p27(Kip1).

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SLIP1, a factor required for activation of histone mRNA translation by the stem-loop binding protein

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The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway

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Post-translational regulation of the tumor suppressor p27(KIP1).

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p27Kip1 represses transcription by direct interaction with p130/E2F4 at the promoters of target genes

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Cell cycle regulation in hematopoietic stem cells

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Cell cycle regulation and hepatocarcinogenesis

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MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

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PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1.

21 January 2018

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A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

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KIS induces proliferation and the cell cycle progression through the phosphorylation of p27Kip1 in leukemia cells

21 January 2018

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PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest

21 January 2018

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Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

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MicroRNAs direct rapid deadenylation of mRNA

21 January 2018

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Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.

21 January 2018

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The human histone gene expression regulator HBP/SLBP is required for histone and DNA synthesis, cell cycle progression and cell proliferation in mitotic cells

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Drosophila stem loop binding protein coordinates accumulation of mature histone mRNA with cell cycle progression

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NELF interacts with CBC and participates in 3' end processing of replication-dependent histone mRNAs.

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Expression and prognostic role of Spy1 as a novel cell cycle protein in hepatocellular carcinoma.

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Decreased expression of p27 protein is associated with advanced tumor stage in hepatocellular carcinoma

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Akt-dependent T198 phosphorylation of cyclin-dependent kinase inhibitor p27kip1 in breast cancer.

31 March 2020

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12 December 2020

Protein expression of p53, p21WAF1, and Rb as prognostic indicators in patients with surgically treated hepatocellular carcinoma.

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12 December 2020

JAB1 expression is associated with inverse expression of p27(kip1) in hepatocellular carcinoma

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12 December 2020

Expression of p27, cyclin E and cyclin A in hepatocellular carcinoma and its clinical significance

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12 December 2020

Identifiers

DOI

10.1038/ONC.2013.536

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24336329%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference