p53 status determines the role of autophagy in pancreatic tumour development (Q39048945)

8 September 2017

p53 status determines the role of autophagy in pancreatic tumour development (English)

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Taranjit Singh Rai

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Kurt Anderson

object named as

Kurt I Anderson

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author name string

Mathias T Rosenfeldt

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8 September 2017

Jim O'Prey

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Colin Nixon

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Gillian MacKay

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Agata Mrowinska

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Amy Au

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Liang Zheng

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Rachel Ridgway

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Peter D Adams

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language of work or name

English

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publication date

4 December 2013

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8 September 2017

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504

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7479

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296-300

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https://scigraph.springernature.com/pub.10.1038/nature12865

8 September 2017

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cites work

Mammalian autophagy: core molecular machinery and signaling regulation

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Autophagy fights disease through cellular self-digestion

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Autophagy: basic principles and relevance to disease

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

21 January 2018

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Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12865

Pancreatic cancers require autophagy for tumor growth

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12865

Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12865

Genetics and biology of pancreatic ductal adenocarcinoma.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12865

Principles and current strategies for targeting autophagy for cancer treatment

21 January 2018

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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

21 January 2018

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12865

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Analysis of macroautophagy by immunohistochemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration.

21 January 2018

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Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer

21 January 2018

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Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer

21 January 2018

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Autophagy mediates the mitotic senescence transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

21 January 2018

1 reference

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Autophagy suppresses tumor progression by limiting chromosomal instability

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE12865

Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

21 January 2018

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Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

21 January 2018

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Successful growth and characterization of mouse pancreatic ductal cells: functional properties of the Ki-RAS(G12V) oncogene

21 January 2018

1 reference

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Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE12865

Splicing DNA-damage responses to tumour cell death.

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24305049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/24305049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE12865

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Dimensions Publication ID

8 September 2017

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