Pharmacokinetics and Pharmacodynamics of Afamelanotide and its Clinical Use in Treating Dermatologic Disorders (Q39072282)

8 September 2017

Pharmacokinetics and Pharmacodynamics of Afamelanotide and its Clinical Use in Treating Dermatologic Disorders (English)

1 reference

8 September 2017

1 reference

1 reference

Elisabeth I Minder

1

1 reference

PubMed ID

28063031

8 September 2017

Jasmin Barman-Aksoezen

series ordinal

2

1 reference

PubMed ID

28063031

8 September 2017

Xiaoye Schneider-Yin

series ordinal

3

1 reference

8 September 2017

6 January 2017

1 reference

Clinical Pharmacokinetics

8 September 2017

1 reference

8 September 2017

56

1 reference

8 September 2017

815-823

1 reference

8 September 2017

8

1 reference

https://scigraph.springernature.com/pub.10.1007/s40262-016-0501-5

8 September 2017

0 references

cites work

The evolution of pro-opiomelanocortin: looking for the invertebrate fingerprints

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Central role of p53 in the suntan response and pathologic hyperpigmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Tyrosinase and related proteins in mammalian pigmentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Melanosome capping of keratinocytes in pigmented reconstructed epidermis--effect of ultraviolet radiation and 3-isobutyl-1-methyl-xanthine on melanogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Molecular characterization of melanocyte stem cells in their niche.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

alpha-MSH tripeptide analogs activate the melanocortin 1 receptor and reduce UV-induced DNA damage in human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Molecular regulation of melanocyte senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

The melanotropic peptide, [Nle4,D-Phe7] alpha-MSH, stimulates human melanoma tyrosinase activity and inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Anti-inflammatory and anti-invasive effects of α-melanocyte-stimulating hormone in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Melanoma cell attachment, invasion, and integrin expression is upregulated by tumor necrosis factor alpha and suppressed by alpha melanocyte stimulating hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Studies on the physiological functions of the melanocortin system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Afamelanotide, an agonistic analog of α-melanocyte-stimulating hormone, in dermal phototoxicity of erythropoietic protoporphyria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Administration of melanotropic peptides during gestation in the rodent.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Enzymological studies of melanotropins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Effect of alpha- and betamelanocyte stimulating hormones on the skin colour of man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Induction of skin tanning by subcutaneous administration of a potent synthetic melanotropin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Activation of the cAMP pathway by variant human MC1R alleles expressed in HEK and in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Evidence for alternate points of attachment for alpha-MSH and its stereoisomer [Nle4, D-Phe7]-alpha-MSH at the melanocortin-1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

[Nle4-D-Phe7]-alpha-melanocyte-stimulating hormone significantly increased pigmentation and decreased UV damage in fair-skinned Caucasian volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Effect of MELANOTAN, [Nle(4), D-Phe(7)]-alpha-MSH, on melanin synthesis in humans with MC1R variant alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

The role of alpha-melanocyte-stimulating hormone in cutaneous biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Skin pigmentation and pharmacokinetics of melanotan-I in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Controlled-release delivery system for the alpha-MSH analog melanotan-I using poloxamer 407.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Pharmacologic response of a controlled-release PLGA formulation for the alpha-melanocyte stimulating hormone analog, Melanotan-I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

An alpha-melanocyte-stimulating hormone analogue in erythropoietic protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Afamelanotide for Erythropoietic Protoporphyria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Systemic photoprotection in solar urticaria with α-melanocyte-stimulating hormone analogue [Nle4-D-Phe7]-α-MSH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Efficacy of the melanocortin analogue Nle4-D-Phe7-α-melanocyte-stimulating hormone in the treatment of patients with Hailey-Hailey disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Beneficial effects of the melanocortin analogue Nle4-D-Phe7-α-MSH in acne vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

The efficacy of afamelanotide and narrowband UV-B phototherapy for repigmentation of vitiligo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

A review of UVA-mediated photosensitivity disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Photodynamic and light independent action of 8 to 2 carboxylic free porphyrins on some haem-enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Quantitation of hydrogen peroxide formed during UV-visible irradiation of protoporphyrin, coproporphyrin and uroporphyrin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Long-term observational study of afamelanotide in 115 patients with erythropoietic protoporphyria.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Indications and limitations of afamelanotide for treating vitiligo-reply.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Complex multipathways alterations and oxidative stress are associated with Hailey-Hailey disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Oxidative stress activation of miR-125b is part of the molecular switch for Hailey-Hailey disease manifestation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Melanoma associated with the use of melanotan-II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

alpha-Melanocyte-stimulating hormone-induced eruptive nevi.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Change in moles linked to use of unlicensed "sun tan jab"

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Antigenicity: Some Molecular Aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

A bioassay for the detection of neutralizing antibodies against the α-melanocyte stimulating hormone analog afamelanotide in patients with erythropoietic protoporphyria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Autoantibodies against neuropeptides are associated with psychological traits in eating disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Pro-opiomelanocortin-Related Peptides, Prohormone Convertases 1 and 2 and the Regulatory Peptide 7B2 are Present in Melanosomes of Human Melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS40262-016-0501-5

Effects of a superpotent melanotropic peptide in combination with solar UV radiation on tanning of the skin in human volunteers

21 January 2018

1 reference

12 December 2020

Mechanisms of phototoxicity in porphyria cutanea tarda and erythropoietic protoporphyria.

1 reference

12 December 2020

alpha-MSH modulates experimental inflammatory bowel disease

1 reference

12 December 2020

In vitro transdermal delivery of a melanotropic peptide through human skin

1 reference

12 December 2020

A review and update on melanocyte stimulating hormone therapy: afamelanotide

1 reference

12 December 2020

Vascular changes in erythropoietic protoporphyria: histopathologic and immunohistochemical study

1 reference

12 December 2020

Eruptive melanocytic naevi following melanotan injection

1 reference

12 December 2020

Immunogenicity of a free synthetic peptide: carrier-conjugation enhances antibody affinity for the native protein

1 reference

12 December 2020

Atypical melanocytic naevi following melanotan injection

1 reference

12 December 2020

A systematic review of treatment options for dermal photosensitivity in erythropoietic protoporphyria

1 reference

12 December 2020

Biological actions of melanocyte-stimulating hormone

1 reference

12 December 2020

Toxicologic studies of a superpotent alpha-melanotropin, [Nle4, D-Phe7]alpha-MSH.

1 reference

12 December 2020

Melanotan-associated melanoma in situ

1 reference

12 December 2020

Melanin biosynthesis patterns following hormonal stimulation.

1 reference

12 December 2020

Evaluation of the immunogenicity of the synthetic α-melanocyte-stimulating hormone (α-MSH) analogue afamelanotide ([Nle4-D-Phe7]-α-MSH, Scenesse®) in erythropoietic protoporphyria patients by ELISA detecting both anti-afamelanotide and anti-α-MSH an

1 reference

12 December 2020

10.1007/S40262-016-0501-5

Identifiers

DOI

1 reference

8 September 2017

1 reference

PubMed ID

28063031