Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer (Q39090185)

9 September 2017

Estrogen receptor β upregulates FOXO3a and causes induction of apoptosis through PUMA in prostate cancer (English)

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9 September 2017

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P Dey

1

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9 September 2017

A Ström

series ordinal

2

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9 September 2017

J-Å Gustafsson

series ordinal

3

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9 September 2017

language of work or name

English

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publication date

30 September 2013

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9 September 2017

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9 September 2017

33

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9 September 2017

33

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9 September 2017

4213-4225

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https://scigraph.springernature.com/pub.10.1038/onc.2013.384

9 September 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein

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miR-155, a Modulator of FOXO3a Protein Expression, Is Underexpressed and Cannot Be Upregulated by Stimulation of HOZOT, a Line of Multifunctional Treg

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Forkhead box transcription factor FOXO3a suppresses estrogen-dependent breast cancer cell proliferation and tumorigenesis

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Estrogen receptor beta deficiency enhances small intestinal tumorigenesis in ApcMin/+ mice

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Enhanced induction of mucin-depleted foci in estrogen receptor {beta} knockout mice

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Aggressive prostate cancer is prevented in ERαKO mice and stimulated in ERβKO TRAMP mice

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Potential role of estrogen receptor beta as a tumor suppressor of epithelial ovarian cancer

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Estrogen receptors β1 and β2 have opposing roles in regulating proliferation and bone metastasis genes in the prostate cancer cell line PC3.

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Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest

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Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D.

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Estrogen receptor-beta activated apoptosis in benign hyperplasia and cancer of the prostate is androgen independent and TNFalpha mediated

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Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations

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Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells

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Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR.

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Estrogen receptor beta2 and beta5 are associated with poor prognosis in prostate cancer, and promote cancer cell migration and invasion.

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5alpha-Androstane-3beta,17beta-diol (3beta-diol), an estrogenic metabolite of 5alpha-dihydrotestosterone, is a potent modulator of estrogen receptor ERbeta expression in the ventral prostrate of adult rats.

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An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth

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The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

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FOXO transcription factors at the interface between longevity and tumor suppression

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Cloning of a novel receptor expressed in rat prostate and ovary

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Selective activation of estrogen receptor-beta transcriptional pathways by an herbal extract.

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Distinct roles of unliganded and liganded estrogen receptors in transcriptional repression

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The dual, opposing roles of estrogen in the prostate.

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ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading

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An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation

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Estrogen receptor β and 17β-hydroxysteroid dehydrogenase type 6, a growth regulatory pathway that is lost in prostate cancer

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Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma

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PUMA, a novel proapoptotic gene, is induced by p53

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Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer.

31 March 2020

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Estrogen receptor beta inhibits angiogenesis and growth of T47D breast cancer xenografts

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Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells.

31 March 2020

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Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells

31 March 2020

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Endothelial NOS, estrogen receptor beta, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer

31 March 2020

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

31 March 2020

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HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1.

31 March 2020

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DAX-1 expression is regulated during mammary epithelial cell differentiation

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2013.384

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release_wehs2duhtfddxmxu3lhzpyijqa

9 September 2017

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24 November 2022

based on heuristic

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