MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways. (Q39095883)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037528%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways (English)

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21 February 2020

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1 reference

8

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Gregory J Goodall

10

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21 February 2020

Philip A Gregory

11

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21 February 2020

author name string

X Li

1

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21 February 2020

S Roslan

2

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21 February 2020

C N Johnstone

3

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J A Wright

4

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21 February 2020

C P Bracken

5

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M Anderson

6

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A G Bert

7

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R L Anderson

9

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21 February 2020

Y Khew-Goodall

12

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language of work or name

English

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publication date

16 September 2013

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21 February 2020

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21 February 2020

volume

33

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21 February 2020

issue

31

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21 February 2020

page(s)

4077-4088

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https://scigraph.springernature.com/pub.10.1038/onc.2013.370

21 February 2020

exact match

0 references

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Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2.

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The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

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The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

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The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

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A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

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A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition

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An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

21 January 2018

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Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

21 January 2018

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Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells

21 January 2018

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miR-200c regulates induction of apoptosis through CD95 by targeting FAP-1

21 January 2018

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EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

21 January 2018

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MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents

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Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancer

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Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

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miR-200 enhances mouse breast cancer cell colonization to form distant metastases

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Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

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MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis

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MicroRNA expression characterizes oligometastasis(es)

21 January 2018

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The miRNA-200 family and miRNA-9 exhibit differential expression in primary versus corresponding metastatic tissue in breast cancer.

21 January 2018

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Down-regulation of the miRNA-200 family at the invasive front of colorectal cancers with degraded basement membrane indicates EMT is involved in cancer progression.

21 January 2018

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MicroRNA-200 family members differentially regulate morphological plasticity and mode of melanoma cell invasion

21 January 2018

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miR-200bc/429 cluster targets PLCgamma1 and differentially regulates proliferation and EGF-driven invasion than miR-200a/141 in breast cancer

21 January 2018

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Targets of miR-200c mediate suppression of cell motility and anoikis resistance

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The miR200 family of microRNAs regulates WAVE3-dependent cancer cell invasion

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miRNA-mRNA integrated analysis reveals roles for miRNAs in primary breast tumors

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Moesin orchestrates cortical polarity of melanoma tumour cells to initiate 3D invasion

21 January 2018

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Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression.

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MicroRNA-200c attenuates tumour growth and metastasis of presumptive head and neck squamous cell carcinoma stem cells.

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miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor

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miR-200b regulates cell migration via Zeb family during mouse palate development.

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21 January 2018

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Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer

21 January 2018

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Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer

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To differentiate or not--routes towards metastasis

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The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2013.370

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037528%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24037528%20AND%20SRC:MED&resulttype=core&format=json