Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma (Q39096897)

9 September 2017

Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma (English)

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9 September 2017

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9 September 2017

6

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9 September 2017

He Liu

1

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9 September 2017

Zhaoyue He

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2

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9 September 2017

Thomas von Rütte

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3

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9 September 2017

Robert E Hunger

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5

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9 September 2017

language of work or name

English

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publication date

1 September 2013

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Science Translational Medicine

9 September 2017

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9 September 2017

5

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9 September 2017

202ra123

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9 September 2017

202

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A novel phenotype with features of basal cell nevus syndrome and basaloid follicular hamartoma syndrome

9 September 2017

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Mutations of the BRAF gene in human cancer

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

The MAPK pathway in melanoma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Deregulated Akt3 activity promotes development of malignant melanoma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy: renovation of cells and tissues

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy in mammalian development and differentiation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy in immunity and inflammation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Deconvoluting the context-dependent role for autophagy in cancer

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Development by self-digestion: molecular mechanisms and biological functions of autophagy

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Induction of autophagy and inhibition of tumorigenesis by beclin 1

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Induction of autophagy during extracellular matrix detachment promotes cell survival

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Extracellular matrix regulation of autophagy

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Chaperone-mediated autophagy is required for tumor growth

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

The landscape of somatic copy-number alteration across human cancers

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Epigenetic events in malignant melanoma.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Biosynthetic FGF-2 is targeted to non-lipid raft microdomains following translocation to the extracellular surface of CHO cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Human skin fibroblasts in vitro differentiate along a terminal cell lineage

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

High frequency of BRAF mutations in nevi

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Modelling melanoma in mice.

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy-deficient mice develop multiple liver tumors

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Measurements of tumor cell autophagy predict invasiveness, resistance to chemotherapy, and survival in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy is a protective mechanism for human melanoma cells under acidic stress

21 January 2018

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https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Resistance of human melanoma cells against the death ligand TRAIL is reversed by ultraviolet-B radiation via downregulation of FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Effects of several flavonoids on the growth of B16F10 and SK-MEL-1 melanoma cell lines: relationship between structure and activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

Autophagy mediates the mitotic senescence transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005864

10.1126/SCITRANSLMED.3005864

21 January 2018

Identifiers

DOI

1 reference

9 September 2017

1 reference