The Protein Neddylation Pathway in Trypanosoma brucei: FUNCTIONAL CHARACTERIZATION AND SUBSTRATE IDENTIFICATION. (Q39107272)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27956554%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

The Protein Neddylation Pathway in Trypanosoma brucei: FUNCTIONAL CHARACTERIZATION AND SUBSTRATE IDENTIFICATION (English)

1 reference

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ubiquitin activating enzyme, putative

29 March 2020

main subject

Trypanosoma brucei

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5 February 2019

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5 February 2019

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5 February 2019

Cullin family/Cullin protein neddylation domain containing protein, putative

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5 February 2019

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6 February 2019

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6 February 2019

ubiquitin-conjugating enzyme E2, putative

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6 February 2019

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6 February 2019

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6 February 2019

ubiquitin-activating enzyme E1, putative

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1 reference

5

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29 March 2020

Shanhui Liao

1

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29 March 2020

author name string

Huiqing Hu

2

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29 March 2020

Tao Wang

3

1 reference

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29 March 2020

Xiaoming Tu

4

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29 March 2020

language of work or name

English

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publication date

12 December 2016

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Journal of Biological Chemistry

29 March 2020

published in

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29 March 2020

volume

292

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issue

3

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29 March 2020

page(s)

1081-1091

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Assembly and maintenance of the flagellum attachment zone filament in Trypanosoma brucei.

29 March 2020

cites work

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Inhibition of NEDD8-activating enzyme induces rereplication and apoptosis in human tumor cells consistent with deregulating CDT1 turnover

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22 June 2018

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NEDD8-targeting drug MLN4924 elicits DNA rereplication by stabilizing Cdt1 in S phase, triggering checkpoint activation, apoptosis, and senescence in cancer cells

22 June 2018

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The small ubiquitin-like modifier (SUMO) is essential in cell cycle regulation in Trypanosoma brucei.

22 June 2018

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Trypanosoma brucei ATG8: structural insights into autophagic-like mechanisms in protozoa

22 June 2018

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Solution structure of Urm1 from Trypanosoma brucei

22 June 2018

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Function and regulation of protein neddylation. 'Protein modifications: beyond the usual suspects' review series

22 June 2018

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Identification of a novel chromosomal passenger complex and its unique localization during cytokinesis in Trypanosoma brucei

22 June 2018

1 reference

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Ribosomal proteins are targets for the NEDD8 pathway

22 June 2018

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A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.

22 June 2018

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A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei

22 June 2018

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22 June 2018

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Analysis of Nedd8-associated polypeptides: a model for deciphering the pathway for ubiquitin-like modifications

22 June 2018

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Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

22 June 2018

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Nedd8 on cullin: building an expressway to protein destruction.

22 June 2018

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Saccharomyces cerevisiae ubiquitin-like protein Rub1 conjugates to cullin proteins Rtt101 and Cul3 in vivo.

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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A Nedd8 conjugation pathway is essential for proteolytic targeting of p27Kip1 by ubiquitination

22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

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22 June 2018

1 reference

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

22 June 2018

1 reference

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Tubulin post-translational modifications and the construction of microtubular organelles in Trypanosoma brucei

22 June 2018

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Flagellar adhesion in Trypanosoma brucei relies on interactions between different skeletal structures in the flagellum and cell body

22 June 2018

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The cooperative roles of PHO80-like cyclins in regulating the G1/S transition and posterior cytoskeletal morphogenesis in Trypanosoma brucei

21 August 2018

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Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels

21 August 2018

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Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei

21 August 2018

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21 August 2018

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21 August 2018

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The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

21 August 2018

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Inhibition of proteasome activity blocks cell cycle progression at specific phase boundaries in African trypanosomes

21 August 2018

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Trypanosoma brucei FLA1 is required for flagellum attachment and cytokinesis

21 August 2018

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12 December 2020

Visualization of detyrosination along single microtubules reveals novel mechanisms of assembly during cytoskeletal duplication in trypanosomes

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12 December 2020

Assembly of the paraflagellar rod and the flagellum attachment zone complex during the Trypanosoma brucei cell cycle

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12 December 2020

Identifiers

DOI

10.1074/JBC.M116.766741

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27956554%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27956554%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

PubMed publication ID

27956554

1 reference