STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas. (Q39115912)

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scientific article published on 5 August 2013

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English	STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas.	scientific article published on 5 August 2013

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6 March 2020

STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett's adenocarcinomas (English)

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6 March 2020

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esophageal squamous cell carcinoma

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Thomas Reinheckel

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6 March 2020

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6 March 2020

David S Klimstra

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S Timme

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S Ihde

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C D Fichter

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V Waehle

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L Bogatyreva

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K Atanasov

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I Kohler

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A Schöpflin

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H Geddert

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G Faller

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L Tang

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D Hauschke

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M Boerries

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M Werner

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S Lassmann

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6 March 2020

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6 March 2020

Getting the message across, STAT! Design principles of a molecular signaling circuit.

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Immunohistochemical analysis of phosphotyrosine signal transducer and activator of transcription 3 and epidermal growth factor receptor autocrine signaling pathways in head and neck cancers and metastatic lymph nodes.

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Expression of activated signal transducer and activator of transcription 3 predicts expression of vascular endothelial growth factor in and angiogenic phenotype of human gastric cancer

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Expression of activated signal transducer and activator of transcription 3 predicts poor clinical outcome in gastric adenocarcinoma

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STAT3 mRNA and protein expression in colorectal cancer: effects on STAT3-inducible targets linked to cell survival and proliferation

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Targeted inhibition of Stat3 with a decoy oligonucleotide abrogates head and neck cancer cell growth

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A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB.

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Combined targeting of epidermal growth factor receptor, signal transducer and activator of transcription-3, and Bcl-X(L) enhances antitumor effects in squamous cell carcinoma of the head and neck.

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Inhibition of STAT-3 results in greater cetuximab sensitivity in head and neck squamous cell carcinoma

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Enhanced sensitivity of pancreatic cancer cells to concurrent inhibition of aberrant signal transducer and activator of transcription 3 and epidermal growth factor receptor or Src.

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Combined blockade of Src kinase and epidermal growth factor receptor with gemcitabine overcomes STAT3-mediated resistance of inhibition of pancreatic tumor growth

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Oesophageal carcinoma

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EGFR-induced cell migration is mediated predominantly by the JAK-STAT pathway in primary esophageal keratinocytes

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Activation of the interleukin-6/STAT3 antiapoptotic pathway in esophageal cells by bile acids and low pH: relevance to barrett's esophagus

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Cancer-related inflammation and Barrett's carcinogenesis: interleukin-6 and STAT3 mediate apoptotic resistance in transformed Barrett's cells

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Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells

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beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma.

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Preface: STAT signaling

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