Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells. (Q39132780)

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4 March 2020

title

Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells (English)

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4 March 2020

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1

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4 March 2020

Eva Crosas-Molist

2

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4 March 2020

Patricia Sancho

3

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4 March 2020

Judit López-Luque

5

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Gustavo Egea

7

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Emilio Ramos

10

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Isabel Fabregat

11

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4 March 2020

author name string

Laia Caja

4

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4 March 2020

Estanislao Navarro

6

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4 March 2020

Raquel Lastra

8

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Teresa Serrano

9

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4 March 2020

language of work or name

English

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publication date

11 October 2013

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4 March 2020

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4 March 2020

volume

58

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issue

6

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4 March 2020

page(s)

2032-2044

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4 March 2020

1 reference

Transforming growth factor-beta activates both pro-apoptotic and survival signals in fetal rat hepatocytes

21 January 2018

1 reference

Differential intracellular signalling induced by TGF-beta in rat adult hepatocytes and hepatoma cells: implications in liver carcinogenesis.

21 January 2018

1 reference

Involvement of EGF receptor and c-Src in the survival signals induced by TGF-beta1 in hepatocytes

21 January 2018

1 reference

TGF-β in epithelial to mesenchymal transition and metastasis of liver carcinoma.

21 January 2018

1 reference

Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer

21 January 2018

1 reference

Blocking transforming growth factor-beta up-regulates E-cadherin and reduces migration and invasion of hepatocellular carcinoma cells

21 January 2018

1 reference

Cytokine regulation networks in the cancer microenvironment

21 January 2018

1 reference

New insights on the role of CXCR4 in cancer metastasis

21 January 2018

1 reference

Stromal cell-derived factor-1/chemokine (C-X-C motif) ligand 12 stimulates human hepatoma cell growth, migration, and invasion.

21 January 2018

1 reference

Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4.

21 January 2018

1 reference

Role of CXCR4/SDF-1 alpha in the migratory phenotype of hepatoma cells that have undergone epithelial-mesenchymal transition in response to the transforming growth factor-beta

21 January 2018

1 reference

Developmental switch from prolonged insulin action to increased insulin sensitivity in protein tyrosine phosphatase 1B-deficient hepatocytes

21 January 2018

1 reference

The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.

21 January 2018

1 reference

Overactivation of the MEK/ERK pathway in liver tumor cells confers resistance to TGF-{beta}-induced cell death through impairing up-regulation of the NADPH oxidase NOX4.

21 January 2018

1 reference

Transforming growth factor-beta signaling promotes hepatocarcinogenesis induced by p53 loss

21 January 2018

1 reference

Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis

21 January 2018

1 reference

Hypotheses on the role of transforming growth factor-beta in the onset and progression of hepatocellular carcinoma

21 January 2018

1 reference

Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B.

21 January 2018

1 reference

Induction of epithelial-mesenchymal transition by transforming growth factor β.

21 January 2018

1 reference

Targeting transforming growth factor (TGF)-betaRI inhibits activation of beta1 integrin and blocks vascular invasion in hepatocellular carcinoma

21 January 2018

1 reference

TGF-β in progression of liver disease

21 January 2018

1 reference

Snail1 suppresses TGF-beta-induced apoptosis and is sufficient to trigger EMT in hepatocytes

21 January 2018

1 reference

Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells

21 January 2018

1 reference

Expression of the chemokine receptor CXCR4 in human hepatocellular carcinoma and its role in portal vein tumor thrombus

21 January 2018

1 reference

Latent bone metastasis in breast cancer tied to Src-dependent survival signals

21 January 2018

1 reference

The TGFBeta pathway as a therapeutic target in cancer.

21 January 2018

1 reference

CXCL12 (SDF1alpha)-CXCR4/CXCR7 pathway inhibition: an emerging sensitizer for anticancer therapies?

21 January 2018

1 reference

Regulatory mechanisms for transforming growth factor beta as an autocrine inhibitor in human hepatocellular carcinoma: implications for roles of smads in its growth

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/HEP.26597

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23813475%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference