Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era. (Q39144075)

9 September 2017

title

Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era. (English)

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9 September 2017

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1

Edward M Behrens

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9 September 2017

Gary A Koretzky

2

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9 September 2017

publication date

19 February 2017

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9 September 2017

published in

Arthritis & Rheumatology

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9 September 2017

volume

69

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9 September 2017

issue

6

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9 September 2017

page(s)

1135-1143

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Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group.

9 September 2017

cites work

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Effect of a chimeric antibody to tumor necrosis factor-alpha on cytokine and physiologic responses in patients with severe sepsis--a randomized, clinical trial.

21 January 2018

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An animal model of hemophagocytic lymphohistiocytosis (HLH): CD8+ T cells and interferon gamma are essential for the disorder

21 January 2018

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Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

21 January 2018

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A Heterozygous RAB27A Mutation Associated with Delayed Cytolytic Granule Polarization and Hemophagocytic Lymphohistiocytosis.

21 January 2018

1 reference

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time.

21 January 2018

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Perforin is a critical physiologic regulator of T-cell activation

21 January 2018

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Interferon-γ mediates anemia but is dispensable for fulminant toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis in mice

21 January 2018

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Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice

21 January 2018

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Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-γ receptor deficiency.

21 January 2018

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Whole-Exome Sequencing Reveals Mutations in Genes Linked to Hemophagocytic Lymphohistiocytosis and Macrophage Activation Syndrome in Fatal Cases of H1N1 Influenza

21 January 2018

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Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.

21 January 2018

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Inflammatory Gene Expression Profile and Defective Interferon-γ and Granzyme K in Natural Killer Cells From Systemic Juvenile Idiopathic Arthritis Patients

21 January 2018

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Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

21 January 2018

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Two randomized trials of canakinumab in systemic juvenile idiopathic arthritis

21 January 2018

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Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis

21 January 2018

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Severe imbalance of IL-18/IL-18BP in patients with secondary hemophagocytic syndrome

21 January 2018

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Protection from inflammatory organ damage in a murine model of hemophagocytic lymphohistiocytosis using treatment with IL-18 binding protein

21 January 2018

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Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.

21 January 2018

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An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

21 January 2018

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Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

21 January 2018

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Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.

21 January 2018

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Macrophage activation syndrome in children with systemic lupus erythematosus and children with juvenile idiopathic arthritis

21 January 2018

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Macrophage activation syndrome as the presenting manifestation of rheumatic diseases in childhood.

21 January 2018

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Ankylosing spondylitis presenting with macrophage activation syndrome.

21 January 2018

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Macrophage activation syndrome: A severe and frequent manifestation of acute pancreatitis in 362 childhood-onset compared to 1830 adult-onset systemic lupus erythematosus patients.

21 January 2018

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Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis.

21 January 2018

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Successful control of juvenile dermatomyositis-associated macrophage activation syndrome and interstitial pneumonia: distinct kinetics of interleukin-6 and -18 levels

21 January 2018

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Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

21 January 2018

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Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy.

21 January 2018

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Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2

21 January 2018

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Preclinical in vivo modeling of cytokine release syndrome induced by ErbB-retargeted human T cells: identifying a window of therapeutic opportunity?

21 January 2018

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Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol

21 January 2018

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Macrophage activation syndrome: a potentially fatal complication of rheumatic disorders

21 January 2018

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Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis.

21 January 2018

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Treatment of Epstein Barr virus-induced haemophagocytic lymphohistiocytosis with rituximab-containing chemo-immunotherapeutic regimens

21 January 2018

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Cell type specific infection of Epstein-Barr virus (EBV) in EBV-associated hemophagocytic lymphohistiocytosis and chronic active EBV infection

21 January 2018

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Hematopoietic stem cell transplantation in hemophagocytic lymphohistiocytosis: a single-center report of 48 patients

21 January 2018

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Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab.

21 January 2018

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Treatment of hemophagocytic lymphohistiocytosis with alemtuzumab in systemic lupus erythematosus

21 January 2018

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Efficacy of cyclosporine A in the treatment of macrophage activation syndrome in juvenile arthritis: report of five cases

21 January 2018

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Adult-onset immunodeficiency in Thailand and Taiwan

21 January 2018

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Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab

21 January 2018

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Higher-dose Anakinra is effective in a case of medically refractory macrophage activation syndrome.

21 January 2018

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Anakinra as first-line disease-modifying therapy in systemic juvenile idiopathic arthritis: report of forty-six patients from an international multicenter series

21 January 2018

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ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice

21 January 2018

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Toxicity management for patients receiving novel T-cell engaging therapies.

21 January 2018

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Adult-onset Still's disease with macrophage activation syndrome successfully treated with a combination of methotrexate and etanercept.

21 January 2018

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Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis

21 January 2018

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Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice.

21 January 2018

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Hyperferritinemia in the critically ill child with secondary hemophagocytic lymphohistiocytosis/sepsis/multiple organ dysfunction syndrome/macrophage activation syndrome: what is the treatment?

21 January 2018

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Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial

21 January 2018

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Is Interleukin-1 Receptor Blockade Ready for Prime Time in Patients With Severe Sepsis and Macrophage Activation Syndrome?

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.40071

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9 September 2017

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