The proteasome inhibitor bortezomib is a potent inducer of zinc finger AN1-type domain 2a gene expression: role of heat shock factor 1 (HSF1)-heat shock factor 2 (HSF2) heterocomplexes (Q39146191)

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scientific article published on 11 March 2014

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English	The proteasome inhibitor bortezomib is a potent inducer of zinc finger AN1-type domain 2a gene expression: role of heat shock factor 1 (HSF1)-heat shock factor 2 (HSF2) heterocomplexes	scientific article published on 11 March 2014

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9 September 2017

The proteasome inhibitor bortezomib is a potent inducer of zinc finger AN1-type domain 2a gene expression: role of heat shock factor 1 (HSF1)-heat shock factor 2 (HSF2) heterocomplexes (English)

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Simone La Frazia

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Antonio Rossi

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Marta Coccia

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Edoardo Trotta

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M Gabriella Santoro

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11 March 2014

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Journal of Biological Chemistry

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12705-12715

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Molecular architecture and assembly of the eukaryotic proteasome

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The ubiquitin proteasome system - implications for cell cycle control and the targeted treatment of cancer

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Development of proteasome inhibitors as research tools and cancer drugs

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Covalent and non-covalent reversible proteasome inhibition

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Post-translational modification of human heat shock factors and their functions: a recent update by proteomic approach

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The ubiquitin-proteasome system meets angiogenesis.

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Regulation of hematopoietic stem cell fate by the ubiquitin proteasome system

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Regulation of cyclooxygenase-2 expression by heat: a novel aspect of heat shock factor 1 function in human cells

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Proteasome inhibitors and modulators of angiogenesis in multiple myeloma

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Ubiquitylation in apoptosis: a post-translational modification at the edge of life and death

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p21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis

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10 September 2017

Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.

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Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans

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Inhibition of the ubiquitin-proteasome system induces stress granule formation.

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Role of ubiquitin- and Ubl-binding proteins in cell signaling

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An arsenite-inducible 19S regulatory particle-associated protein adapts proteasomes to proteotoxicity

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A phase I and pharmacologic trial of two schedules of the proteasome inhibitor, PS-341 (bortezomib, velcade), in patients with advanced cancer

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Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies

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Arsenite-inducible RNA-associated protein (AIRAP) protects cells from arsenite toxicity

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Roles of the heat shock transcription factors in regulation of the heat shock response and beyond

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10 September 2017

Heat shock factor 2 is activated during mouse heart development

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Disruption of heat shock factor 1 reveals an essential role in the ubiquitin proteolytic pathway

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Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

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Induction of ferritin and heat shock proteins by prostaglandin A1 in human monocytes. Evidence for transcriptional and post-transcriptional regulation

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Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones, and negative regulators

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Inhibition of nuclear factor kappa B by prostaglandin A1: an effect associated with heat shock transcription factor activation

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10 September 2017

Activation of heat shock gene transcription by heat shock factor 1 involves oligomerization, acquisition of DNA-binding activity, and nuclear localization and can occur in the absence of stress

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10 September 2017

Human heat shock factors 1 and 2 are differentially activated and can synergistically induce hsp70 gene transcription

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Characterization of constitutive HSF2 DNA-binding activity in mouse embryonal carcinoma cells

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Selection of new HSF1 and HSF2 DNA-binding sites reveals difference in trimer cooperativity

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Heat shock response and protein degradation: regulation of HSF2 by the ubiquitin-proteasome pathway

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Attenuation of the heat shock response in HeLa cells is mediated by the release of bound heat shock transcription factor and is modulated by changes in growth and in heat shock temperatures

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Bortezomib induces autophagic death in proliferating human endothelial cells.

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Hsp70 is required for optimal cell proliferation in mouse A6 mesoangioblast stem cells

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Bortezomib mediates antiangiogenesis in multiple myeloma via direct and indirect effects on endothelial cells

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Proteasome inhibition leads to the activation of all members of the heat-shock-factor family

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12 December 2020

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Heat Shock Factor 2 (HSF2) Contributes to Inducible Expression ofhspGenes through Interplay with HSF1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24619424

12 December 2020

based on heuristic

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Hypoxia-inducible transcription factor-1 alpha determines sensitivity of endothelial cells to the proteosome inhibitor bortezomib

1 reference

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12 December 2020

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Roles of heat shock factor 1 and 2 in response to proteasome inhibition: consequence on p53 stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/24619424

12 December 2020

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10.1074/JBC.M113.513242

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619424%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619424%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24619424%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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