Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells (Q39147029)

9 September 2017

Celastrol induced DNA damage, cell cycle arrest, and apoptosis in human rheumatoid fibroblast-like synovial cells (English)

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9 September 2017

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Zengtao Xu

1

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9 September 2017

Guosheng Wu

2

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9 September 2017

Xu Wei

3

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9 September 2017

Xiuping Chen

4

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9 September 2017

Yitao Wang

5

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9 September 2017

Lidian Chen

6

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9 September 2017

1 January 2013

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The American Journal of Chinese Medicine

9 September 2017

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9 September 2017

41

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9 September 2017

3

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9 September 2017

615-628

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Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.

9 September 2017

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Mechanisms of p34cdc2 regulation

21 January 2018

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Apoptosis in rheumatoid arthritis

21 January 2018

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https://api.crossref.org/works/10.1142%2FS0192415X13500432

Celastrol targets mitochondrial respiratory chain complex I to induce reactive oxygen species-dependent cytotoxicity in tumor cells

21 January 2018

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Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB

21 January 2018

1 reference

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Gene transfer of tissue inhibitor of metalloproteinases-3 reverses the inhibitory effects of TNF-alpha on Fas-induced apoptosis in rheumatoid arthritis synovial fibroblasts

21 January 2018

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Celastrol causes apoptosis and cell cycle arrest in rat glioma cells

21 January 2018

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KHC-4 anti-cancer effects on human PC3 prostate cancer cell line

21 January 2018

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Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways

21 January 2018

1 reference

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Fibroblast biology. Synovial fibroblasts in rheumatoid arthritis: leading role or chorus line?

21 January 2018

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Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells

21 January 2018

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Rheumatoid arthritis synovial fluid fibroblasts express TRAIL-R2 (DR5) that is functionally active.

21 January 2018

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Therapeutic opportunities in fibroblasts in inflammatory arthritis

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Animal cell cycles and their control

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The role and therapeutic implications of fibroblast-like synoviocytes in inflammation and cartilage erosion in rheumatoid arthritis

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HSP90 inhibitor, celastrol, arrests human monocytic leukemia cell U937 at G0/G1 in thiol-containing agents reversible way

21 January 2018

1 reference

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Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia. Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining

21 January 2018

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Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

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Microarchitecture and protective mechanisms in synovial tissue from clinically and arthroscopically normal knee joints

21 January 2018

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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

21 January 2018

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JAB1 determines the response of rheumatoid arthritis synovial fibroblasts to tumor necrosis factor-alpha

21 January 2018

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Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90.

21 January 2018

1 reference

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Ganoderma lucidum extract induces G1 cell cycle arrest, and apoptosis in human breast cancer cells.

21 January 2018

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Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities

21 January 2018

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Corydalis yanhusuo W.T. Wang extract inhibits MCF-7 cell proliferation by inducing cell cycle G2/M arrest

21 January 2018

1 reference

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Dehydrocorydaline inhibits breast cancer cells proliferation by inducing apoptosis in MCF-7 cells

21 January 2018

1 reference

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Pathogenesis of rheumatoid arthritis: the role of synoviocytes

21 January 2018

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A novel Hsp90 inhibitor to disrupt Hsp90/Cdc37 complex against pancreatic cancer cells

21 January 2018

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Role of triptolide in cell proliferation, cell cycle arrest, apoptosis and histone methylation in multiple myeloma U266 cells

21 January 2018

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Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines

21 January 2018

1 reference

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Biologic activity of triptolide in t(8;21) acute myeloid leukemia cells.

21 January 2018

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Celastrol-induced apoptosis in human HaCaT keratinocytes involves the inhibition of NF-κB activity

21 January 2018

1 reference

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10.1142/S0192415X13500432

21 January 2018

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DOI

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9 September 2017

1 reference