Cyclophosphamide triggers follicle activation and "burnout"; AS101 prevents follicle loss and preserves fertility (Q39151472)

9 September 2017

Cyclophosphamide triggers follicle activation and "burnout"; AS101 prevents follicle loss and preserves fertility (English)

1 reference

9 September 2017

Lital Kalich-Philosoph

1

1 reference

9 September 2017

Hadassa Roness

2

1 reference

9 September 2017

Alon Carmely

3

1 reference

9 September 2017

Michal Fishel-Bartal

4

1 reference

9 September 2017

Hagai Ligumsky

5

1 reference

9 September 2017

Shoshana Paglin

6

1 reference

9 September 2017

Ido Wolf

7

1 reference

9 September 2017

Hannah Kanety

8

1 reference

9 September 2017

Benjamin Sredni

9

1 reference

9 September 2017

Dror Meirow

10

1 reference

9 September 2017

language of work or name

English

0 references

publication date

1 May 2013

1 reference

Science Translational Medicine

9 September 2017

1 reference

9 September 2017

5

1 reference

9 September 2017

185ra62

1 reference

9 September 2017

185

1 reference

Morphological study of the ovaries of leukaemic children

9 September 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Toxicity of chemotherapy and radiation on female reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Fertility preservation in female patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Quantitative assessment of the impact of chemotherapy on ovarian follicle reserve and stromal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Structural and ultrastructural study of the ovary in childhood leukemia after successful treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Inhibition of the c-Abl-TAp63 pathway protects mouse oocytes from chemotherapy-induced death

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

A novel ovarian xenografting model to characterize the impact of chemotherapy agents on human primordial follicle reserve.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Effects of cyclophosphamide and buthionine sulfoximine on ovarian glutathione and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Preserving ovarian function in patients receiving cyclophosphamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

How do chemotherapeutic agents damage the ovary?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Reproductive toxicity of cyclophosphamide in the C57BL/6N mouse: 1. Effects on ovarian structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

On regenerating the ovary and generating controversy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Molecular mechanisms underlying the activation of mammalian primordial follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Awakening the oocyte: controlling primordial follicle development

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

mTOR signaling in the control of activation of primordial follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Mechanisms maintaining the dormancy and survival of mammalian primordial follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Oogenesis: transcriptional regulators and mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Suppression of ovarian follicle activation in mice by the transcription factor Foxo3a

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Foxo3 is a PI3K-dependent molecular switch controlling the initiation of oocyte growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

PDK1 signaling in oocytes controls reproductive aging and lifespan by manipulating the survival of primordial follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Activation of dormant ovarian follicles to generate mature eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Cyclophosphamide promotes cell survival via activation of intracellular signaling in cultured cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

A new immunomodulating compound (AS-101) with potential therapeutic application

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Bone marrow-sparing and prevention of alopecia by AS101 in non-small-cell lung cancer patients treated with carboplatin and etoposide

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Ammonium trichloro(dioxoethylene-o,o')tellurate (AS101) sensitizes tumors to chemotherapy by inhibiting the tumor interleukin 10 autocrine loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Immunomodulating tellurium compounds as anti-cancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

The immunomodulator AS101 induces growth arrest and apoptosis in multiple myeloma: association with the Akt/survivin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

The effects of radiotherapy and chemotherapy on female reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Relevance of breast cancer cell lines as models for breast tumours: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Klotho: a tumor suppressor and a modulator of the IGF-1 and FGF pathways in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Anovulation in the prevention of cytotoxic-induced follicular attrition and ovarian failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Reproduction post-chemotherapy in young cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Initiation in vitro of growth of bovine primordial follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

FSH and growth factors affect the growth and endocrine function in vitro of granulosa cells of bovine preantral follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Initiation of growth of baboon primordial follicles in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Studies in vivo and in vitro on the initiation of follicle growth in the bovine ovary.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

mTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

A two-step serum-free culture system supports development of human oocytes from primordial follicles in the presence of activin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Restoration of ovulatory cycles by young ovarian grafts in aging mice: potentiation by long-term ovariectomy decreases with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Early massive follicle loss and apoptosis in heterotopically grafted newborn mouse ovaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Protective effect of the immunomodulator AS101 against cyclophosphamide-induced testicular damage in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

In vitro and in vivo activity of AS101 against West Nile virus (WNV).

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Staying alive: PI3K pathway promotes primordial follicle activation and survival in response to 3MC-induced ovotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Ovarian follicular growth and development in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Regulation of ovarian function: the role of anti-Müllerian hormone

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Control of mammalian oocyte growth and early follicular development by the oocyte PI3 kinase pathway: new roles for an old timer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Pregnancy after Transplantation of Cryopreserved Ovarian Tissue in a Patient with Ovarian Failure after Chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Fertility preservation in girls and young women

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

American Society of Clinical Oncology recommendations on fertility preservation in cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Live birth after transplantation of frozen-thawed ovarian tissue after bilateral oophorectomy for benign disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Serum anti-mullerian hormone levels reflect the size of the primordial follicle pool in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

Characterizing the ovotoxicity of cyclophosphamide metabolites on cultured mouse ovaries

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3005402

10.1126/SCITRANSLMED.3005402

21 January 2018

Identifiers

DOI

1 reference

9 September 2017

1 reference