Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM. (Q39155459)

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29 February 2020

title

Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM (English)

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29 February 2020

main subject

stem cell self-renewal

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2

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29 February 2020

Camila Oliveira Rodini

5

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29 February 2020

author name string

Hideo Shigeishi

1

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29 February 2020

Luke Gammon

3

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29 February 2020

Helena Emich

4

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29 February 2020

Emilios Gemenetzidis

6

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29 February 2020

Bilal Fazil

7

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29 February 2020

Masaru Sugiyama

8

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Nobuyuki Kamata

9

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29 February 2020

Ian C Mackenzie

10

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publication date

1 October 2013

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number of pages

11

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based on heuristic

inferred from page(s)

published in

Stem Cells

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volume

31

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issue

10

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page(s)

2073-2083

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

29 February 2020

cites work

1 reference

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Prospective identification of tumorigenic breast cancer cells

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Phenotypic characterization of human colorectal cancer stem cells

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Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

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Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

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Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma

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Highly purified CD44+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells

21 January 2018

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CD44 variant isoforms in head and neck squamous cell carcinoma progression

21 January 2018

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Hyaluronan-CD44v3 interaction with Oct4-Sox2-Nanog promotes miR-302 expression leading to self-renewal, clonal formation, and cisplatin resistance in cancer stem cells from head and neck squamous cell carcinoma

21 January 2018

1 reference

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21 January 2018

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The characterization of a human RHAMM cDNA: conservation of the hyaluronan-binding domains

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Overexpression of the receptor for hyaluronan-mediated motility, correlates with expression of microtubule-associated protein in human oral squamous cell carcinomas.

21 January 2018

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The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells

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The epithelial-mesenchymal transition generates cells with properties of stem cells

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Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer.

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Retention of intrinsic stem cell hierarchies in carcinoma-derived cell lines.

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The renaissance of GSK3

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21 January 2018

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Glycogen synthase kinase 3 beta: can it be a target for oral cancer

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Snail-induced down-regulation of DeltaNp63alpha acquires invasive phenotype of human squamous cell carcinoma

21 January 2018

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21 January 2018

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21 January 2018

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Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

21 January 2018

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CD44 staining of cancer stem-like cells is influenced by down-regulation of CD44 variant isoforms and up-regulation of the standard CD44 isoform in the population of cells that have undergone epithelial-to-mesenchymal transition

21 January 2018

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Role of microRNAs in the regulation of breast cancer stem cells

21 January 2018

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Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways

21 January 2018

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Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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CD44 regulates cell migration in human colon cancer cells via Lyn kinase and AKT phosphorylation

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Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility [published erratum appears in J Cell Biol 1992 Aug;118(3):753]

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CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression

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Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

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Bone morphogenetic protein 7 in the development and treatment of bone metastases from breast cancer

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The Wnt inhibitory factor 1 restoration in prostate cancer cells was associated with reduced tumor growth, decreased capacity of cell migration and invasion and a reversal of epithelial to mesenchymal transition

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/STEM.1418

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29 February 2020

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