Disease-regulated local IL-10 gene therapy diminishes synovitis and cartilage proteoglycan depletion in experimental arthritis. (Q39159292)

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9 March 2020

title

Disease-regulated local IL-10 gene therapy diminishes synovitis and cartilage proteoglycan depletion in experimental arthritis (English)

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9 March 2020

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Fons van de Loo

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author name string

Eline A Vermeij

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Miranda B Bennink

3

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Onno J Arntz

4

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Inger Gjertsson

5

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Peter L E M van Lent

6

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Wim B van den Berg

7

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Marije I Koenders

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language of work or name

English

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publication date

15 July 2014

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Annals of the Rheumatic Diseases

9 March 2020

published in

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volume

74

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page(s)

2084-2091

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issue

11

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Immunogenicity of anti-TNF biologic therapies for rheumatoid arthritis

9 March 2020

cites work

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Application of a disease-regulated promoter is a safer mode of local IL-4 gene therapy for arthritis.

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Disease-dependent local IL-10 production ameliorates collagen induced arthritis in mice

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Regulatory role of interleukin 10 in joint inflammation and cartilage destruction in murine streptococcal cell wall (SCW) arthritis. More therapeutic benefit with IL-4/IL-10 combination therapy than with IL-10 treatment alone.

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Blocking of interleukin-17 during reactivation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and interleukin-1.

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The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation.

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Suppressor of cytokine signalling protein SOCS3 expression is increased at sites of acute and chronic inflammation

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Effects of interleukin-10 on chemokine KC gene expression by mouse peritoneal macrophages in response to Candida albicans

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Role of the complement system in rheumatoid arthritis and psoriatic arthritis: relationship with anti-TNF inhibitors

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The priming effect of C5a on monocytes is predominantly mediated by the p38 MAPK pathway.

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IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression

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21 January 2018

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25028707%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

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