The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts. (Q39163272)

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3 March 2020

title

The PDK1 master kinase is over-expressed in acute myeloid leukemia and promotes PKC-mediated survival of leukemic blasts (English)

1 reference

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3 March 2020

1 reference

acute myeloid leukemia

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3

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3 March 2020

Rhys Morgan

4

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3 March 2020

Alex Tonks

5

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3 March 2020

author name string

Joanna Zabkiewicz

1

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3 March 2020

Lorna Pearn

2

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3 March 2020

Alan K Burnett

6

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3 March 2020

Richard L Darley

7

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publication date

13 December 2013

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3 March 2020

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3 March 2020

volume

99

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issue

5

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page(s)

858-864

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Clonal evolution of acute leukemia genomes

3 March 2020

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An immunohistochemical perspective of PPAR beta and one of its putative targets PDK1 in normal ovaries, benign and malignant ovarian tumours

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Phosphoinositide 3-kinase/Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia.

10 September 2017

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Serum and glucocorticoid-regulated protein kinases: variations on a theme

10 September 2017

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Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer

10 September 2017

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10 September 2017

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Essential role of PDK1 in regulating cell size and development in mice

10 September 2017

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10 September 2017

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10 September 2017

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21 August 2018

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21 August 2018

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21 August 2018

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Constitutive cytoplasmic localization of p21(Waf1/Cip1) affects the apoptotic process in monocytic leukaemia.

21 August 2018

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21 August 2018

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Transformation of mammary epithelial cells by 3-phosphoinositide-dependent protein kinase-1 (PDK1) is associated with the induction of protein kinase Calpha.

21 August 2018

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Inhibition of PDK-1 activity causes a reduction in cell proliferation and survival

21 August 2018

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Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis

21 August 2018

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12 December 2020

The role of 3-phosphoinositide-dependent protein kinase 1 in activating AGC kinases defined in embryonic stem cells

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12 December 2020

Transformation of mammary epithelial cells by 3-phosphoinositide- dependent protein kinase-1 activates beta-catenin and c-Myc, and down-regulates caveolin-1

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12 December 2020

The role of PKC and PDK1 in monocyte lineage specification by Ras

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12 December 2020

10.3324/HAEMATOL.2013.096487

Identifiers

DOI

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3 March 2020

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3 March 2020

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