IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells (Q39189621)

9 September 2017

IGFBP-2 nuclear translocation is mediated by a functional NLS sequence and is essential for its pro-tumorigenic actions in cancer cells (English)

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9 September 2017

W J Azar

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9 September 2017

S Zivkovic

series ordinal

2

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9 September 2017

G A Werther

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3

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9 September 2017

V C Russo

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4

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9 September 2017

language of work or name

English

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publication date

25 February 2013

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9 September 2017

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9 September 2017

33

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9 September 2017

5

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9 September 2017

578-588

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https://scigraph.springernature.com/pub.10.1038/onc.2012.630

9 September 2017

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cites work

Cellular actions of the insulin-like growth factor binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Significant expression of IGFBP2 in breast cancer compared with benign lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor binding protein-2 is a novel therapeutic target associated with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

IIp45, an insulin-like growth factor binding protein 2 (IGFBP-2) binding protein, antagonizes IGFBP-2 stimulation of glioma cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Novel stimulatory role for insulin-like growth factor binding protein-2 in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Bimolecular interaction of insulin-like growth factor (IGF) binding protein-2 with alphavbeta3 negatively modulates IGF-I-mediated migration and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Silencing of insulin-like growth factor-binding protein-2 in human glioblastoma cells reduces both invasiveness and expression of progression-associated gene CD24.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Intracellular colocalization and interaction of IGF-binding protein-2 with the cyclin-dependent kinase inhibitor p21CIP1/WAF1 during growth inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its growth-promoting actions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Distinct patterns of insulin-like growth factor binding protein (IGFBP)-2 and IGFBP-3 expression in oxidant exposed lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

IGFBP-2 enhances VEGF gene promoter activity and consequent promotion of angiogenesis by neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Peri/nuclear localization of intact insulin-like growth factor binding protein-2 and a distinct carboxyl-terminal IGFBP-2 fragment in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nucleocytoplasmic transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nucleocytoplasmic transport: the soluble phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear targeting sequences--a consensus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

A short amino acid sequence able to specify nuclear location

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Sequence requirements for nuclear location of simian virus 40 large-T antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Karyopherins and nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Biophysical characterization of interactions involving importin-alpha during nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor binding protein-3 prevents retinoid receptor heterodimerization: implications for retinoic acid-sensitivity in human breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor binding protein-5 interacts with the vitamin D receptor and modulates the vitamin D response in osteoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 share a common nuclear transport pathway in T47D human breast carcinoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear import of insulin-like growth factor-binding protein-3 and -5 is mediated by the importin beta subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

A functional nuclear localization signal in insulin-like growth factor binding protein-6 mediates its nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Sequence and characterization of cytoplasmic nuclear protein import factor p97

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nucleocytoplasmic shuttling factors including Ran and CRM1 mediate nuclear export of NFAT In vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

A novel mechanism of E2F1 regulation via nucleocytoplasmic shuttling: determinants of nuclear import and export.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear location signals in polyoma virus large-T.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Identification of the human c-myc protein nuclear translocation signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear translocation of viral Jun but not of cellular Jun is cell cycle dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

The cell cycle-dependent nuclear import of v-Jun is regulated by phosphorylation of a serine adjacent to the nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear Import of Creb and AP-1 Transcription Factors Requires Importin-β1 and Ran but Is Independent of Importin-α

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Identification of essential sequences for cellular localization in BRMS1 metastasis suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Recovery of mitogenic activity of a growth factor mutant with a nuclear translocation sequence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Sequence requirements for synthetic peptide-mediated translocation to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Classical nuclear localization signals: definition, function, and interaction with importin alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor binding protein-2 binding to extracellular matrix plays a critical role in neuroblastoma cell proliferation, migration, and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Structural basis of high-affinity nuclear localization signal interactions with importin-α

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Cell membrane association of insulin-like growth factor binding protein-2 (IGFBP-2) in the rat brain olfactory bulb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor (IGF) binding protein 2 functions coordinately with receptor protein tyrosine phosphatase β and the IGF-I receptor to regulate IGF-I-stimulated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Identification and functional analysis of NOL7 nuclear and nucleolar localization signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear import of Pin1 is mediated by a novel sequence in the PPIase domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Facilitated nuclear transport of histone H1 and other small nucleophilic proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Isolation of a protein that is essential for the first step of nuclear protein import

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

The C-terminal nuclear localization signal of the sex-determining region Y (SRY) high mobility group domain mediates nuclear import through importin beta 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Structural basis for nuclear import complex dissociation by RanGTP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

The insulin-like growth factor system and its pleiotropic functions in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Structural determinants of ligand and cell surface binding of insulin-like growth factor-binding protein-3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Dissection of a nuclear localization signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Fibroblast growth factor 2 reactivates G1 checkpoint in SK-N-MC cells via regulation of p21, inhibitor of differentiation genes (Id1-3), and epithelium-mesenchyme transition-like events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Insulin-like growth factor binding protein-2 binds to cell surface proteoglycans in the rat brain olfactory bulb.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Effect of insulin-like growth factor binding protein-1 on integrin signalling and the induction of apoptosis in human breast cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Ku80 can translocate to the nucleus independent of the translocation of Ku70 using its own nuclear localization signal

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Identification of cytosolic factors required for nuclear location sequence-mediated binding to the nuclear envelope

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Nuclear localization signal receptor affinity correlates with in vivo localization in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

Estrogen and insulin modulation of intracellular insulin-like growth factor binding proteins in human breast cancer cells: possible involvement in lysosomal hydrolases oversecretion

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.630

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.630

1 reference

release_jeytsjcpgbbwlfgwatromqweda

9 September 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/jeytsjcpgbbwlfgwatromqweda

mapped directly with Wikidata item

24 November 2022

based on heuristic

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