Design, synthesis and biological evaluation of indolizine derivatives as HIV-1 VIF-ElonginC interaction inhibitors (Q39200129)

9 September 2017

Design, synthesis and biological evaluation of indolizine derivatives as HIV-1 VIF-ElonginC interaction inhibitors (English)

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9 September 2017

Wenlin Huang

1

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9 September 2017

Tao Zuo

2

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9 September 2017

Hongwei Jin

3

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9 September 2017

Zhenming Liu

4

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9 September 2017

Zhenjun Yang

5

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9 September 2017

Xianghui Yu

6

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9 September 2017

Liangren Zhang

7

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9 September 2017

Lihe Zhang

8

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9 September 2017

3 February 2013

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9 September 2017

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9 September 2017

17

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9 September 2017

2

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9 September 2017

221-243

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https://scigraph.springernature.com/pub.10.1007/s11030-013-9424-3

9 September 2017

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21 January 2018

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Hypermutation of HIV-1 DNA in the Absence of the Vif Protein

21 January 2018

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Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

21 January 2018

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Cytidine deaminases as a weapon against retroviruses and a new target for antiviral therapy

21 January 2018

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VHL-box and SOCS-box domains determine binding specificity for Cul2-Rbx1 and Cul5-Rbx2 modules of ubiquitin ligases

21 January 2018

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A zinc-binding region in Vif binds Cul5 and determines cullin selection

21 January 2018

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Expression of HIV-1 accessory protein Vif is controlled uniquely to be low and optimal by proteasome degradation

21 January 2018

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Assembly of HIV-1 Vif-Cul5 E3 ubiquitin ligase through a novel zinc-binding domain-stabilized hydrophobic interface in Vif.

21 January 2018

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21 January 2018

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Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G

21 January 2018

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Baculiferins A-O, O-sulfated pyrrole alkaloids with anti-HIV-1 activity, from the Chinese marine sponge Iotrochota baculifera

21 January 2018

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SAR and Lead Optimization of an HIV-1 Vif-APOBEC3G Axis Inhibitor.

21 January 2018

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Small-molecule inhibition of human immunodeficiency virus type 1 replication by targeting the interaction between Vif and ElonginC.

21 January 2018

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Recent progress in synthesis and bioactivity studies of indolizines

21 January 2018

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Structural insight into the human immunodeficiency virus Vif SOCS box and its role in human E3 ubiquitin ligase assembly

21 January 2018

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Molecular insight into the conformational dynamics of the Elongin BC complex and its interaction with HIV-1 Vif.

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/23378232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Three-dimensional structure of HIV-1 VIF constructed by comparative modeling and the function characterization analyzed by molecular dynamics simulation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23378232

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11030-013-9424-3

1 reference

9 September 2017

1 reference