Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells (Q39237839)

10 September 2017

Blockade of Myd88 signaling induces antitumor effects by skewing the immunosuppressive function of myeloid-derived suppressor cells (English)

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10 September 2017

Eun-Hye Hong

1

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10 September 2017

Sun-Young Chang

2

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10 September 2017

Bo-Ra Lee

3

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10 September 2017

Yun-Sun Kim

4

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10 September 2017

Jeong-Mi Lee

5

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10 September 2017

Chang-Yuil Kang

6

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10 September 2017

Mi-Na Kweon

7

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10 September 2017

Hyun-Jeong Ko

8

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10 September 2017

language of work or name

English

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publication date

19 December 2012

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International Journal of Cancer

10 September 2017

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10 September 2017

132

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10 September 2017

12

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10 September 2017

2839-2848

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Ligand-independent toll-like receptor signals generated by ectopic overexpression of MyD88 generate local and systemic antitumor immunity

10 September 2017

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Pathogen recognition and innate immunity

21 January 2018

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Amplifying TLR-MyD88 signals within tumor-specific T cells enhances antitumor activity to suboptimal levels of weakly immunogenic tumor antigens

21 January 2018

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Tumor immunotherapy using bone marrow-derived dendritic cells overexpressing Toll-like receptor adaptors.

21 January 2018

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Enhanced efficacy of therapeutic cancer vaccines produced by co-treatment with Mycobacterium tuberculosis heparin-binding hemagglutinin, a novel TLR4 agonist

21 January 2018

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Antitumor activity and immune response induction of a dual agonist of Toll-like receptors 7 and 8.

21 January 2018

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Myeloid-derived suppressor cells as regulators of the immune system

21 January 2018

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Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodes

21 January 2018

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Myeloid-derived suppressor cells down-regulate L-selectin expression on CD4+ and CD8+ T cells

21 January 2018

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Cancer-expanded myeloid-derived suppressor cells induce anergy of NK cells through membrane-bound TGF-beta 1.

21 January 2018

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IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.

21 January 2018

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Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells

21 January 2018

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Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

21 January 2018

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Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.

21 January 2018

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Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression

21 January 2018

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Fas signal promotes lung cancer growth by recruiting myeloid-derived suppressor cells via cancer cell-derived PGE2.

21 January 2018

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Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma

21 January 2018

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Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells

21 January 2018

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Tumor-induced tolerance and immune suppression depend on the C/EBPbeta transcription factor.

21 January 2018

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CD40-targeted recombinant adenovirus significantly enhances the efficacy of antitumor vaccines based on dendritic cells and B cells

21 January 2018

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Pharmacologic inhibition of myeloid differentiation factor 88 (MyD88) prevents left ventricular dilation and hypertrophy after experimental acute myocardial infarction in the mouse

21 January 2018

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Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function

21 January 2018

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Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes

21 January 2018

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In vivo antigen delivery by a Salmonella typhimurium type III secretion system for therapeutic cancer vaccines.

21 January 2018

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A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model

21 January 2018

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MyD88 signal is required for more efficient induction of Ag-specific adaptive immune responses and antitumor resistance in a human papillomavirus E7 DNA vaccine model

21 January 2018

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Adjuvant effect of HER-2/neu-specific adenoviral vector stimulating CD8⁺ T and natural killer cell responses on anti-HER-2/neu antibody therapy for well-established breast tumors in HER-2/neu transgenic mice.

21 January 2018

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Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance.

21 January 2018

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Targeting immune suppressing myeloid-derived suppressor cells in oncology.

21 January 2018

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GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

21 January 2018

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IL-17 promotes tumor development through the induction of tumor promoting microenvironments at tumor sites and myeloid-derived suppressor cells

21 January 2018

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The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells

21 January 2018

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Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells

21 January 2018

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Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells

21 January 2018

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Translational control of inducible nitric oxide synthase expression by arginine can explain the arginine paradox

21 January 2018

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Myeloid-derived suppressor cells inhibit T-cell activation by depleting cystine and cysteine

21 January 2018

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The immunosuppressive surface ligand CD200 augments the metastatic capacity of squamous cell carcinoma.

21 January 2018

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Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

21 January 2018

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Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells

21 January 2018

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Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.27974

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10 September 2017

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