MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells. (Q39246695)

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17 February 2020

title

MDA5 detects the double-stranded RNA replicative form in picornavirus-infected cells (English)

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17 February 2020

3

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17 February 2020

Richard Virgen-Slane

5

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Frank J. M. van Kuppeveld

17 February 2020

10

object named as

Frank J M van Kuppeveld

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17 February 2020

8

Bert L Semler

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17 February 2020

author name string

Qian Feng

1

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17 February 2020

Stanleyson V Hato

2

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17 February 2020

Jan Zoll

4

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17 February 2020

Alys Peisley

6

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17 February 2020

Sun Hur

7

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17 February 2020

Ronald P van Rij

9

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17 February 2020

publication date

8 November 2012

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17 February 2020

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17 February 2020

volume

2

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17 February 2020

issue

5

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17 February 2020

page(s)

1187-1196

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Distinct roles of protein kinase R and toll-like receptor 3 in the activation of astrocytes by viral stimuli

17 February 2020

cites work

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12 December 2020

Characterization of transgenic mice with targeted disruption of the catalytic domain of the double-stranded RNA-dependent protein kinase, PKR.

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Structure of poliovirus replicative intermediate RNA. Electron microscope analysis of RNA cross-linked in vivo with psoralen derivative

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Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus

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12 December 2020

Regulation of innate immunity through RNA structure and the protein kinase PKR.

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Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

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Structural and functional characterization of the coxsackievirus B3 CRE(2C): role of CRE(2C) in negative- and positive-strand RNA synthesis

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Dipyridamole reversibly inhibits mengovirus RNA replication

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A proline-rich region in the coxsackievirus 3A protein is required for the protein to inhibit endoplasmic reticulum-to-golgi transport

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Genetic analysis of a hydrophobic domain of coxsackie B3 virus protein 2B: a moderate degree of hydrophobicity is required for a cis-acting function in viral RNA synthesis

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RNase L releases a small RNA from HCV RNA that refolds into a potent PAMP.

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Basis for regulated RNA cleavage by functional analysis of RNase L and Ire1p

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

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12 December 2020

Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5

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12 December 2020

MDA5 and MAVS mediate type I interferon responses to coxsackie B virus.

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12 December 2020

Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.

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12 December 2020

(+)RNA viruses rewire cellular pathways to build replication organelles

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12 December 2020

RIG-I-like receptors: cytoplasmic sensors for non-self RNA.

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12 December 2020

Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses

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12 December 2020

Polyadenylation of genomic RNA and initiation of antigenomic RNA in a positive-strand RNA virus are controlled by the same cis-element

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Saffold virus, a human Theiler's-like cardiovirus, is ubiquitous and causes infection early in life

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12 December 2020

Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C.

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12 December 2020

Effects of RNase L mutations associated with prostate cancer on apoptosis induced by 2',5'-oligoadenylates

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12 December 2020

MDA-5 recognition of a murine norovirus

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12 December 2020

Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity

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12 December 2020

Engineered picornavirus VPg-RNA substrates: analysis of a tyrosyl-RNA phosphodiesterase activity

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12 December 2020

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

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12 December 2020

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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12 December 2020

Activation of MDA5 requires higher-order RNA structures generated during virus infection

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12 December 2020

Mengovirus leader is involved in the inhibition of host cell protein synthesis

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12 December 2020

A PCR primer bank for quantitative gene expression analysis

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12 December 2020

The mengovirus leader protein blocks interferon-α/β gene transcription and inhibits activation of interferon regulatory factor 3

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12 December 2020