Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line (Q39250474)

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title

Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line (English)

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5

Per Svenningsson

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author name string

Ebba Gregorsson Lundius

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Nikolas Stroth

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Vladana Vukojević

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Lars Terenius

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language of work or name

English

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publication date

6 December 2012

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Journal of Neurochemistry

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published in

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volume

124

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issue

3

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page(s)

410-417

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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cites work

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Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease

21 January 2018

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Parkinson's disease: mechanisms and models

21 January 2018

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Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease

21 January 2018

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6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease

21 January 2018

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Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons

21 January 2018

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Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity

21 January 2018

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

21 January 2018

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Pael receptor is involved in dopamine metabolism in the nigrostriatal system

21 January 2018

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

21 January 2018

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Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation

21 January 2018

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Altered dopamine signaling and MPTP resistance in mice lacking the Parkinson's disease-associated GPR37/parkin-associated endothelin-like receptor

21 January 2018

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Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress

21 January 2018

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Inhibition of protein kinase C induces differentiation in Neuro-2a cells

21 January 2018

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Pael-R is accumulated in Lewy bodies of Parkinson's disease

21 January 2018

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Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

21 January 2018

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Differentiation of mouse Neuro 2A cells into dopamine neurons

21 January 2018

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Expanding insights on the involvement of endoplasmic reticulum stress in Parkinson's disease

21 January 2018

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Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss

21 January 2018

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Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JNC.12081

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10 September 2017

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