Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage (Q39253252)

10 September 2017

Glucocerebrosidase inhibition causes mitochondrial dysfunction and free radical damage (English)

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Derralynn A Hughes

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Nicholas W. Wood

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Nicholas William Wood

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John Anthony Hardy

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John Hardy

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Michael W J Cleeter

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Kai-Yin Chau

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Caroline Gluck

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Atul Mehta

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J Mark Cooper

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Anthony Henry Schapira

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23 October 2012

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Neurochemistry International

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describes a project that uses

10 September 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3550523/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Glucocerebrosidase deficiency in substantia nigra of parkinson disease brains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3550523

CNS expression of glucocerebrosidase corrects alpha-synuclein pathology and memory in a mouse model of Gaucher-related synucleinopathy

10 September 2017

1 reference

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Gaucher disease glucocerebrosidase and α-synuclein form a bidirectional pathogenic loop in synucleinopathies

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3550523

Alpha-synuclein interacts with Glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases

10 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3550523

DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease

10 September 2017

1 reference

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Chaperone-mediated autophagy markers in Parkinson disease brains

10 September 2017

1 reference

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Molecular and clinical prodrome of Parkinson disease: implications for treatment

10 September 2017

1 reference

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The risk of Parkinson's disease in type 1 Gaucher disease

10 September 2017

1 reference

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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

10 September 2017

1 reference

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Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

10 September 2017

1 reference

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Phenotype, diagnosis, and treatment of Gaucher's disease

10 September 2017

1 reference

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Leukocyte beta-glucosidase in homozygotes and heterozygotes for Gaucher disease

10 September 2017

1 reference

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Anatomic and disease specificity of NADH CoQ1 reductase (complex I) deficiency in Parkinson's disease

10 September 2017

1 reference

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PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death

10 September 2017

1 reference

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In vitro accumulation of glucocerebroside in neuroblastoma cells: a model for study of Gaucher disease pathobiology

14 September 2017

1 reference

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Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress

25 September 2017

1 reference

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Alpha-synuclein-glucocerebrosidase interactions in pharmacological Gaucher models: a biological link between Gaucher disease and parkinsonism.

17 June 2018

1 reference

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Proteasomal inhibition causes loss of nigral tyrosine hydroxylase neurons.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3550523

Neuropathology provides clues to the pathophysiology of Gaucher disease

21 August 2018

1 reference

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Differences in toxicity of the catechol-O-methyl transferase inhibitors, tolcapone and entacapone to cultured human neuroblastoma cells

21 August 2018

1 reference

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Imaging mitochondrial function in intact cells.

21 August 2018

1 reference

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Proteasomal function is impaired in substantia nigra in Parkinson's disease

21 August 2018

1 reference

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21 August 2018

Mitochondrial diseases

1 reference

12 December 2020

Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant

1 reference

12 December 2020

Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia

1 reference

12 December 2020

beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell

1 reference

12 December 2020

Etiology of Parkinson's disease

1 reference

12 December 2020

10.1016/J.NEUINT.2012.10.010

Identifiers

DOI

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10 September 2017

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10 September 2017

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