Lactotransferrin acts as a tumor suppressor in nasopharyngeal carcinoma by repressing AKT through multiple mechanisms (Q39258777)

10 September 2017

Lactotransferrin acts as a tumor suppressor in nasopharyngeal carcinoma by repressing AKT through multiple mechanisms (English)

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10 September 2017

M Deng

1

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10 September 2017

W Zhang

2

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10 September 2017

H Tang

3

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10 September 2017

Q Ye

4

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10 September 2017

Q Liao

5

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Y Zhou

6

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10 September 2017

M Wu

7

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10 September 2017

W Xiong

8

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10 September 2017

Y Zheng

9

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10 September 2017

X Guo

10

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10 September 2017

Z Qin

11

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10 September 2017

W He

12

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10 September 2017

M Zhou

13

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10 September 2017

J Xiang

14

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10 September 2017

X Li

15

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10 September 2017

J Ma

16

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10 September 2017

G Li

17

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10 September 2017

language of work or name

English

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publication date

15 October 2012

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10 September 2017

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32

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4273-4283

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36

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https://scigraph.springernature.com/pub.10.1038/onc.2012.434

10 September 2017

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Post-initiation chemopreventive effects of dietary bovine lactoferrin on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in female A/J mice.

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Oral lactoferrin inhibits growth of established tumors and potentiates conventional chemotherapy.

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Growth suppression effects of recombinant adenovirus expressing human lactoferrin on cervical cancer in vitro and in vivo

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Isolation of a lactoferrin cDNA clone and its expression in human breast cancer

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Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice

21 January 2018

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Human lactoferrin controls the level of retinoblastoma protein and its activity

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Signaling Transduction Network Mediated by Tumor Suppressor/Susceptibility Genes in NPC.

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Lactotransferrin: a candidate tumor suppressor-Deficient expression in human nasopharyngeal carcinoma and inhibition of NPC cell proliferation by modulating the mitogen-activated protein kinase pathway

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"New"-clear functions of PDK1: beyond a master kinase in the cytosol?

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c-Jun regulates phosphoinositide-dependent kinase 1 transcription: implication for Akt and protein kinase C activities and melanoma tumorigenesis

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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Toward unraveling the complexity of simple epithelial keratins in human disease

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Keratins as markers that distinguish normal and tumor-derived mammary epithelial cells

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A keratin cytoskeletal protein regulates protein synthesis and epithelial cell growth

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14-3-3 proteins associate with phosphorylated simple epithelial keratins during cell cycle progression and act as a solubility cofactor

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Keratin binding to 14-3-3 proteins modulates keratin filaments and hepatocyte mitotic progression

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Phosphorylation of human keratin 18 serine 33 regulates binding to 14-3-3 proteins

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Differential expression of Epstein-Barr virus-encoded RNA and several tumor-related genes in various types of nasopharyngeal epithelial lesions and nasopharyngeal carcinoma using tissue microarray analysis

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Lactoferrin and cancer disease prevention.

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Perturbations of the AKT signaling pathway in human cancer

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AKT signaling in normal and malignant cells

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Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence

21 January 2018

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Proteomics of breast cancer: enhanced expression of cytokeratin19 in human epidermal growth factor receptor type 2 positive breast tumors

21 January 2018

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Ligation of beta4 integrins activates PKB/Akt and ERK1/2 by distinct pathways-relevance of the keratin filament

21 January 2018

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The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development

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Role of 14-3-3 proteins in eukaryotic signaling and development

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Silencing of Lactotransferrin expression by methylation in prostate cancer progression

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miR-216b suppresses tumor growth and invasion by targeting KRAS in nasopharyngeal carcinoma

21 January 2018

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[Preparation and properties of lactosiderophilin (lactotransferrin) of human milk]

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.434

Inhibition of azoxymethane initiated colon tumor and aberrant crypt foci development by bovine lactoferrin administration in F344 rats

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.434

Genetic and epigenetic alterations of LTF at 3p21.3 in nasopharyngeal carcinoma.

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.434

Consistent downregulation of human lactoferrin gene, in the common eliminated region 1 on 3p21.3, following tumor growth in severe combined immunodeficient (SCID) mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.434

Lactoferrin down-regulates G1 cyclin-dependent kinases during growth arrest of head and neck cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.434

Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells

31 March 2020

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https://api.crossref.org/works/10.1038%2FONC.2012.434

Human delta-lactoferrin is a transcription factor that enhances Skp1 (S-phase kinase-associated protein) gene expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.434

Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.434

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.434

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Dimensions Publication ID

10 September 2017

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