Type-II NADH Dehydrogenase (NDH-2): a promising therapeutic target for antitubercular and antibacterial drug discovery (Q39284340)

10 September 2017

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title

Type-II NADH Dehydrogenase (NDH-2): a promising therapeutic target for antitubercular and antibacterial drug discovery (English)

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10 September 2017

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Satheeshkumar Sellamuthu

1

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10 September 2017

Meenakshi Singh

2

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10 September 2017

Ashok Kumar

3

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10 September 2017

Sushil Kumar Singh

4

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10 September 2017

language of work or name

English

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publication date

4 May 2017

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Expert Opinion on Therapeutic Targets

10 September 2017

published in

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10 September 2017

volume

21

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10 September 2017

issue

6

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10 September 2017

page(s)

559-570

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Modulation of the immune response to Mycobacterium tuberculosis during malaria/M. tuberculosis co-infection

10 September 2017

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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis

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Diarylquinolines are bactericidal for dormant mycobacteria as a result of disturbed ATP homeostasis

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The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis

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Novel FMN-containing rotenone-insensitive NADH dehydrogenase from Trypanosoma brucei mitochondria: isolation and characterization

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The malaria parasite type II NADH:quinone oxidoreductase: an alternative enzyme for an alternative lifestyle

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Type II NADH: menaquinone oxidoreductase of Mycobacterium tuberculosis

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Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients

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21 January 2018

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Structure of the bacterial type II NADH dehydrogenase: a monotopic membrane protein with an essential role in energy generation

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Infrared spectroscopic evidence of a redox-dependent conformational change involving ion binding residue NqrB-D397 in the Na(+)-pumping NADH:quinone oxidoreductase from Vibrio cholerae.

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Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria

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Substrate-Protein Interactions of Type II NADH:Quinone Oxidoreductase from Escherichia coli.

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Comparison of lipid and detergent enzyme environments for identifying inhibitors of membrane-bound energy-transducing proteins.

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Annotated compound data for modulators of detergent-solubilised or lipid-reconstituted respiratory type II NADH dehydrogenase activity obtained by compound library screening

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Cytochrome bd terminal oxidase

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Steady-state kinetics and inhibitory action of antitubercular phenothiazines on mycobacterium tuberculosis type-II NADH-menaquinone oxidoreductase (NDH-2).

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Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species

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New insights into type II NAD(P)H:quinone oxidoreductases

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Neuroleptic drugs in the treatment of tuberculosis: Minimal inhibitory concentrations of different phenothiazines against Mycobacterium tuberculosis.

21 January 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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Gramicidin S identified as a potent inhibitor for cytochromebd-type quinol oxidase

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10.1080/14728222.2017.1327577

21 January 2018

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