The role of waixenicin A as transient receptor potential melastatin 7 blocker. (Q39295809)

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11 February 2020

title

The role of waixenicin A as transient receptor potential melastatin 7 blocker (English)

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11 February 2020

2

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author name string

Byung J Kim

1

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11 February 2020

Young K Kwon

3

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Insuk So

4

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11 February 2020

Seon J Kim

5

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publication date

25 September 2012

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Basic and Clinical Pharmacology and Toxicology

11 February 2020

published in

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volume

112

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issue

2

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page(s)

83-89

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TRP channels as cellular sensors

11 February 2020

cites work

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LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability

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TRP-PLIK, a bifunctional protein with kinase and ion channel activities

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Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine.

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W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity

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A case for interstitial cells of Cajal as pacemakers and mediators of neurotransmission in the gastrointestinal tract

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Melastatin-type transient receptor potential channel 7 is required for intestinal pacemaking activity.

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Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer

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Evidence that TRPM7 is required for breast cancer cell proliferation.

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Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels

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A Ca(2+)-activated Cl(-) conductance in interstitial cells of Cajal linked to slow wave currents and pacemaker activity

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Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract

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TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity

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Expression cloning of TMEM16A as a calcium-activated chloride channel subunit

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TMEM16A confers receptor-activated calcium-dependent chloride conductance

21 January 2018

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Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

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Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation

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Role of voltage-gated potassium channels in cancer.

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TRP proteins and cancer

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Ion channels and cancer

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Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7.

21 January 2018

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Channel function is dissociated from the intrinsic kinase activity and autophosphorylation of TRPM7/ChaK1.

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TRPM7 channel is regulated by magnesium nucleotides via its kinase domain.

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Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase

21 January 2018

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A key role for TRPM7 channels in anoxic neuronal death

21 January 2018

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Defective skeletogenesis with kidney stone formation in dwarf zebrafish mutant for trpm7.

21 January 2018

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TRPM7 facilitates cholinergic vesicle fusion with the plasma membrane.

21 January 2018

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TRPM7 ion channels are required for sustained phosphoinositide 3-kinase signaling in lymphocytes

21 January 2018

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21 January 2018

Identifiers

DOI

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11 February 2020

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